2022
DOI: 10.3389/fbioe.2022.998571
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A novel dual MoS2/FeGA quantum dots endowed injectable hydrogel for efficient photothermal and boosting chemodynamic therapy

Abstract: Due to its responsiveness to the tumour microenvironment (TME), chemodynamic therapy (CDT) based on the Fenton reaction to produce cytotoxic reactive oxygen species (ROS) to destroy tumor has drawn more interest. However, the Fenton’s reaction potential for therapeutic use is constrained by its modest efficacy. Here, we develop a novel injectable hydrogel system (FMH) on the basis of FeGA/MoS2 dual quantum dots (QDs), which uses near-infrared (NIR) laser in order to trigger the synergistic catalysis and photot… Show more

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Cited by 5 publications
(4 citation statements)
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“…Q 0 represents the input power caused by the light absorbed by the solution and cuvette, I represents a laser power density of 808 nm, and A 808 represents the absorbance of g-CNQDs@AgNSs at 808 nm. Eqn (2) shows the linear relationship between Àln(DT/DT max ) and cooling time t, where t is the heat transfer time constant of the system. m and C w in eqn (3) are the mass of the solution (1.9182 g) and the specific heat capacity of water (4.2 J (g C) À1 ), respectively.…”
Section: Photothermal Conversion Efficiency and Photothermal Stabilit...mentioning
confidence: 99%
See 1 more Smart Citation
“…Q 0 represents the input power caused by the light absorbed by the solution and cuvette, I represents a laser power density of 808 nm, and A 808 represents the absorbance of g-CNQDs@AgNSs at 808 nm. Eqn (2) shows the linear relationship between Àln(DT/DT max ) and cooling time t, where t is the heat transfer time constant of the system. m and C w in eqn (3) are the mass of the solution (1.9182 g) and the specific heat capacity of water (4.2 J (g C) À1 ), respectively.…”
Section: Photothermal Conversion Efficiency and Photothermal Stabilit...mentioning
confidence: 99%
“…1 The use of diversified nanosystems can effectively remove malignant tumors with specific microenvironments of weak acidity, hypoxia and high hydrogen peroxide content. 2 In addition, owing to the enhanced permeability and retention effect of tumor tissues, the nanomaterial-based oncology diagnostic system can more effectively function in the tumors. 3 Recently, many novel therapies based on nanomaterials such as phototherapy, chemotherapy and immunotherapy have emerged.…”
Section: Introductionmentioning
confidence: 99%
“…Common semiconductor materials used for photothermal conversion include MoS 2 , CuS, TiO 2 , and Bi 2 S 3 . FeGA/MoS 2 quantum dots prepared by Liu et al [58] . can be injected into a hydrogel system and exhibit sound catalytic and photothermal effects under near‐infrared light.…”
Section: Types Of Photothermal Agentsmentioning
confidence: 99%
“…Common semiconductor materials used for photothermal conversion include MoS 2 , CuS, TiO 2 , and Bi 2 S 3 . FeGA/MoS 2 quantum dots prepared by Liu et al [58] can be injected into a hydrogel system and exhibit sound catalytic and photothermal effects under near-infrared light. MoS 2 has a catalytic effect, and Mo 4 + in quantum dots accelerates the reduction of Fe 3 + , improving the efficiency of the Fenton reaction and demonstrating the synergistic effect of photothermal therapy (PTT) and chemical dynamic therapy (CDT).…”
Section: Semiconductor Photothermal Agentmentioning
confidence: 99%