A Novel Electrochemical Sensor Based on Plastic Antibodies for Vitamin D3 Detection in Real Samples

Kia, Solmaz; Bohlooli, Shahab; Bahar, Shahriyar

doi:10.1109/jsen.2019.2903090

Cited by 19 publications

(8 citation statements)

References 17 publications

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“…A selective molecular imprinted polymer, p-phenylenediamineÀ resorcinol, was synthesized by electropolymerization in the presence of vitamin D 3 molecules on the screen-printed carbon electrode (SPCE) surface followed by a film deposition on the electrode surface that suppresses the reduction of ferricyanide. This sensor showed a lower detection limit of 1×10 À 12 M with a linear response range of 1×10 11 -2×10 9 M. [37] Her team used a hybrid imprinted polymer to create a highly sensitive electrochemical sensor for another Vitamin D 3 detection study. Multi-walled carbon nanotubes (MWCNTs) were added to the medium during the process of creating the vitamin D 3 absorbent molecular imprinted polymer (MIP), which was then combined with binder graphite powder and neicosane using carbon paste electrodes, with a linear response range of 5×10 À 8 À 7 It was quite efficient for real samples with ×10 À 6 M and lower detection limit of 3×10 À 8 M. [38]…”

Section: Electrochemical Sensors Made With Modified Polymersmentioning

confidence: 99%

“…A selective molecular imprinted polymer, p‐phenylenediamine−resorcinol, was synthesized by electropolymerization in the presence of vitamin D 3 molecules on the screen‐printed carbon electrode (SPCE) surface followed by a film deposition on the electrode surface that suppresses the reduction of ferricyanide. This sensor showed a lower detection limit of 1×10 −12 M with a linear response range of 1×10 11 –2×10 9 M [37] . Her team used a hybrid imprinted polymer to create a highly sensitive electrochemical sensor for another Vitamin D 3 detection study.…”

Section: Electrochemical Sensors Used To Measure Vitamin D3mentioning

confidence: 99%

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Recent Point of Care (PoC) Electrochemical Testing Trends of New Diagnostics Platforms for Vitamin D

Kirazoğlu,

Benli

2023

ChemistrySelect

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Recent advancements in electrochemical sensors for the detection of vitamins, particularly vitamin D, have drawn a lot of attention due to their outstanding advantages of simplicity and high sensitivity. For the purpose of detecting vitamin D in this circumstance, recent research has focused on developing electrochemical sensors. Although there is always space for improvement, electrochemical sensors for vitamin D detection and its transformation into point‐of‐care devices have made great strides lately. For example, the development of innovative electrode materials that can increase sensitivity and selectivity continues to garner a lot of interest. New suggestions on adsorptive detections using vitamin D carriers like nanoclays or hydroxyapatite‐clay composites are being developed. These biosensors hold huge potential for the detection of cheap, disposable, and biodegradable solutions. Also, the biosensor could monitor the depletion of vitamin levels, providing a real‐time platform for the Internet of Medical Things, fifth‐generation wireless communications, and smartphone‐based electrochemical sensors. Currently, electrochemical sensors based on smartphones have been proposed to detect using various biomarkers for monitoring several changes in glucose, etc. We believe smartphone‐based electrochemical sensors and adsorptive sensing platforms provides a novel way toward point‐of‐care tests for identifying especially vitamin D deficiency and real‐time monitoring

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Section: Electrochemical Sensors Made With Modified Polymersmentioning

confidence: 99%

Section: Electrochemical Sensors Used To Measure Vitamin D3mentioning

confidence: 99%

Recent Point of Care (PoC) Electrochemical Testing Trends of New Diagnostics Platforms for Vitamin D

Kirazoğlu,

Benli

2023

ChemistrySelect

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“…Binding sites for the target molecule are generated via MIP recognition, which enhanced the sensor's LOD and selectivity. The MIP of p-phenylenediamine-resorcinol combination was coated on the screen-printed carbon electrode (SPCE), and different variables affecting response current were investigated and tuned to provide a linear response range of 1 Â 10 À11 -2 Â 10 À9 M and a lower LOD of 1 Â 10 À12 M (Kia et al 2019).…”

Section: Detection Of Vit Amentioning

confidence: 99%

“…Over (Manoj et al 2021) 2018; Anusha et al 2020). Several varieties of electrodes have also been explored, like ITO-coated glass, GCE, SPCE, and carbon cloth (CC) (Sarkar et al 2018) (Chauhan et al 2019;Kia et al 2019) by various research groups across the globe.…”

Section: Remarksmentioning

confidence: 99%

Advances in electrochemical and optical sensing techniques for vitamins detection: a review

Kumari¹,

Vyas²,

Kumar

2021

ISSS J Micro Smart Syst

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Vitamins are essential nutrients that aid in metabolism, cell growth, and the appropriate functioning of other biomolecules. They are required for the proper functioning of various systems in human body. Both vitamin shortage and excess can pave the way for a variety of illnesses. They enter the body via food and supplements eaten, making it critical to measure the vitamin concentrations in food, medicines, and biological fluids. The concentrations of these vitamins are determined using a variety of techniques. The performance measure of the techniques like selectivity, sensitivity, and limit of detection is crucial in their utilization. Among the many techniques of determination, electrochemical sensing and optical sensing have garnered widespread interest because of their potential to improve performance. Additionally, the introduction of innovative materials has added a lot of benefits to sensing. The aim of this article is to summarize significant work toward recent improvements in electrochemical and optical methods for detecting different vitamins. Additionally, it attempts to assess the gaps in vitamin sensing in order to encourage researchers to fill such gaps that will benefit the community.

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“…Hence, it is essential to keep assessing the level of vitamin D at regular intervals. The electrochemical detection of vitamin D3 has been performed using various polymers, metal, and carbon materials. ,− The electrochemical sensor prepared by coating fullerene-C 60 and copper–nickel nanocomposite on glassy carbon electrode showed a linearity range of 1.25–475 μM and a LOD of 0.0025 μM. In the presence of spiked molecules, a good anti-interference ability was also observed suggesting the specificity of the sensor .…”

Section: Introductionmentioning

confidence: 99%

High-Performance, Nitrogen-Doped, Carbon-Nanotube-Based Electrochemical Sensor For Vitamin D3 Detection

Bora

Mandal

Chandra

2022

ACS Appl. Bio Mater.

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With the fast changing lifestyle, vitamin D deficiency is becoming extremely common. Therefore, development of economical, efficient, and fast sensors for vitamin D is the need of the hour. Carbon-based nanomaterials are extensively explored in sensing of variety of biomolecules. In the present study, an antibody-free, highly sensitive, carbon-nanotube-based, highly responsive vitamin D3 sensor is reported. Nitrogen-doped carbon nanotubes are utilized to overcome the limiting factor of hydrophobic character of pure carbon. The synthesized N-doped CNTs showed a specific surface area of 24 m 2 /g. The surface charges of vitamin D3 and the vitamin D3/NCNT complex are found to be −20 and −6.4 mV, respectively, by zeta potential measurements. The sensor is able to deliver high performance in the concentration range of 0−10 nM, with a limit of detection of 16 pM. The response study indicated the sensitivity value as 0.000495 mA/cm 2 nM. The sensor is also able to show a higher selectivity toward vitamin D3 in comparison to other biomolecules. The long-term stability, reproducibility, good linear range, and ultralow detection capability of the sensor are also reported.

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A Novel Electrochemical Sensor Based on Plastic Antibodies for Vitamin D3 Detection in Real Samples

Cited by 19 publications

References 17 publications

Recent Point of Care (PoC) Electrochemical Testing Trends of New Diagnostics Platforms for Vitamin D

Recent Point of Care (PoC) Electrochemical Testing Trends of New Diagnostics Platforms for Vitamin D

Advances in electrochemical and optical sensing techniques for vitamins detection: a review

High-Performance, Nitrogen-Doped, Carbon-Nanotube-Based Electrochemical Sensor For Vitamin D3 Detection

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