A Novel Embolization Technique for Renal Hemorrhage Complication by Autologous Fat Tissue

A Novel Embolization Technique to Stem Hemorrhage Complications and Cancer

“…This new molecule, called LGIOC (Lithium-gamma-linolenic acid conjugated to an oily lymphographic agent), when injected close to the tumor feeding vessel completely blocked all the tumor feeding vessels without any effect on normal blood vessels (Figures 2, 3). In this instance, the gamma-linolenic acid used is also a lipid (fat) but is different from the subcutaneous fat used by Ari et al (2). It is possible that the subcutaneous fat used by Ari et al (2) also contains some amount of gamma-linolenic acid, but this needs to be confirmed by further analysis.…”

“…Of more than 170 transcripts expressed in the endothelium, 70 were differentially expressed, including 46 that were specifically increased in tumor-associated endothelium (7), suggesting that there are significant differences in gene expression profiles in endothelium derived from normal and tumor vessels. It is possible that LGIOC [and possibly, the subcutaneous fat tissue used by Ari et al (2)] can stimulate some of the genes and/or receptors in the endothelium of the tumor blood vessels, which may have a role in the occlusion of the tumor vessels observed in our study. Thus, there is seems to be a significant role for subcutaneous fat and LGIOC and similar lipids in specifically occluding abnormal vessels (tumor feeding vessels, arterio-venous malformations, or vessels that rupture and bleed during some procedures).…”

“…Using this subcutaneous fat tissue embolization method, the authors could successfully stop the bleeding in two patients. In addition, they demonstrated that the treatment option was safe and reliable for PCNL (2). The advantages of the technique used by the authors are that the embolization could be achieved quickly without the guidewire ever being moved, and the technique seems to be quickly employed to embolize the bleeding point rapidly.…”

“…Given the versatility of the embolization procedure, Ari et al (2) utilized the subcutaneous fat tissue taken with the subcutaneous fascia from the femoral site to stop the bleeding complication from the PCNL. Using this subcutaneous fat tissue embolization method, the authors could successfully stop the bleeding in two patients.…”

Successful angioembolization with autologous subcutaneous fat in an open book pelvic fracture

“…Recently, Arı et al . [ 13 ] used subcutaneous fat embolization for treating a renal artery perforation during percutaneous nephrolithotomy. In contrast with these reports, we used this method not for treating a complication but the situation itself.…”