A novel galanin receptor 1a gene in zebrafish: Tissue distribution, developmental expression roles in nutrition regulation

Li, Linfang; Wei, Shulei; Huang, Qiaoyan; Dong, Feng; Zhang, Shicui; Liu, Zhenhui

doi:10.1016/j.cbpb.2012.12.004

Cited by 23 publications

(23 citation statements)

References 73 publications

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“…rerio were purchased from the local commercial market. Culturing of adult individuals for subsequent sampling of fertilized eggs was carried out as previously described by Li et al (). Briefly, healthy adult fish (two females: one male) were selected to produce embryos.…”

Section: Methodsmentioning

confidence: 99%

Comparative studies of zebrafish Danio rerio lipoprotein lipase (lpl) and hepatic lipase (lipc) genes belonging to the lipase gene family: evolution and expression pattern

Dong

Huang

Liu

et al. 2014

Journal of Fish Biology

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In this study, bioinformatics analysis, tissue distribution and developmental expression pattern of lipoprotein lipase (lpl) and hepatic lipase (lipc) in zebrafish Danio rerio are reported. In adult D. rerio, lpl was highly expressed in liver. This is remarkably different from the tissue expression pattern of LPL in mammals, which is not detected in the adult liver. The expression of lipc was liver specific, which is consistent with that in mammals. During embryogenesis, lpl mRNA was increased gradually in concentration from 0.5 hpf (hour post fertilization) to 6 dpf (days post fertilization), but lipc was not expressed at the early stage of the embryo until 3 dpf. In situ hybridization further displayed the expression pattern of lpl mainly restricted to the head region including cells surrounding the mouth opening, branchial arches, pectoral fin and lateral line neuromast, whereas lipc was mainly restricted to the liver and part of head regions including lens. This lays a foundation for further investigation of lpl or lipc function and evolution in fishes.

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Section: Methodsmentioning

confidence: 99%

Comparative studies of zebrafish Danio rerio lipoprotein lipase (lpl) and hepatic lipase (lipc) genes belonging to the lipase gene family: evolution and expression pattern

Dong

Huang

Liu

et al. 2014

Journal of Fish Biology

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“…Central injections of galanin stimulate feeding in Cypriniformes (both goldfish de Pedro et al, 1995; Volkoff and Peter, 2001b, and tench, Tinca tinca Guijarro et al, 1999). In goldfish, brain galanin mRNA expression is not affected by fasting but increases post-prandially in unfed fish (Unniappan et al, 2004) and in zebrafish, fasting up-regulates brain mRNA expression of galanin receptors (Li et al, 2013). These data suggest that the galanin system is involved in the regulation of feeding in Cypriniformes, and perhaps other fish.…”

Section: Hormones Involved In Food Intakementioning

confidence: 99%

The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge

2016

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Fish are the most diversified group of vertebrates and, although progress has been made in the past years, only relatively few fish species have been examined to date, with regards to the endocrine regulation of feeding in fish. In fish, as in mammals, feeding behavior is ultimately regulated by central effectors within feeding centers of the brain, which receive and process information from endocrine signals from both brain and peripheral tissues. Although basic endocrine mechanisms regulating feeding appear to be conserved among vertebrates, major physiological differences between fish and mammals and the diversity of fish, in particular in regard to feeding habits, digestive tract anatomy and physiology, suggest the existence of fish- and species-specific regulating mechanisms. This review provides an overview of hormones known to regulate food intake in fish, emphasizing on major hormones and the main fish groups studied to date.

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“…To investigate the expression pattern of galr2a and galr2b in zebrafish, we first performed whole-mount in situ RNA hybridization with galr2a and galr2b. In contrast to the expression of zebrafish galr1a and galr1b, which are known to be expressed in the intestine and brain (galr1a), and all tissues (galr1b), respectively, [9], expression of galr2a and galr2b is restricted to CNS of zebrafish embryos. We found that galr2a was expressed at very low levels in a restricted area of the brain including the subpallium (Fig.…”

Section: Galr2a and Galr2b Is Specifically Expressed In The Zebrafishmentioning

confidence: 81%

“…4). At 3 dpf, all galr2b:EGFP + cells are labeled by anti-Hu antibody, indicating that galr2b:EGFP + cells are 9 postmitotic neurons (Fig. 4A-C).…”

Section: Distribution Of Galr2b:egfp + Cells and Their Interaction Wimentioning

confidence: 90%

“…Recent phylogeny and synteny analysis of the gene family have shown that zebrafish GALR2 is subdivided into GALR2a and GALR2b [7]. A recent study has shown that galr1a expression is mainly restricted to the brain and intestines, while galr1b mRNA was present in all tissues [9]. However, nothing has been reported about GALR2a and GALR2b in the zebrafish CNS.…”

Section: Introductionmentioning

confidence: 97%

See 1 more Smart Citation

Distribution of galanin receptor 2b neurons and interaction with galanin in the zebrafish central nervous system

Kim

Jeong

Kim

et al. 2016

Neuroscience Letters

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A novel galanin receptor 1a gene in zebrafish: Tissue distribution, developmental expression roles in nutrition regulation

Cited by 23 publications

References 73 publications

Comparative studies of zebrafish Danio rerio lipoprotein lipase (lpl) and hepatic lipase (lipc) genes belonging to the lipase gene family: evolution and expression pattern

Comparative studies of zebrafish Danio rerio lipoprotein lipase (lpl) and hepatic lipase (lipc) genes belonging to the lipase gene family: evolution and expression pattern

The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge

Distribution of galanin receptor 2b neurons and interaction with galanin in the zebrafish central nervous system

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