A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis

Zwitterionic silver nanoparticle based antibacterial eye drops for efficient therapy of bacterial keratitis

“…The test methods and procedures were according to the literature. 40 In brief, the HCECs were incubated for 24 h in a 96-well plate, and the ZP@Ag-drops with different concentrations were pipetted into each well and cultured for another 24 and 48 h. The CCK-8 was used and the optical density (OD) values of the mixed solution were measured and recorded with a microplate reader. The control group added the same amount of the medium with only CCK-8.…”

Syntheses and polymerization of monoterpene-based (meth)acrylates: IBO(M)A as a relevant monomer for industrial applications

“…These components were chosen to form a resin matrix with minimized polymerization shrinkage and stress, along with enhanced resistance to degradation, making it suitable for use as an intraocular lens in postoperative treatments. 146…”

“…The bulky structure of IBOMA resulted in hindered drug release, attributed to the effect of steric hindrance obstructing the diffusion pathway. 146…”

New Approaches to Overcoming Antimicrobial Resistance in Endophthalmitis

“…Another proposed technique is to use an IOL loaded with antibiotics (moxifloxacin, gatifloxacin) and anti-inflammatories (ketorolac). The latter would allow a sustained and extended drug release with the challenge of avoiding a negative effect on the lens’ physical properties or on the surrounding ocular tissues [ 127 , 128 , 129 , 130 , 131 , 132 ].…”