A novel graphene oxide‐based fluorescence method for detection of urine glycosaminoglycans
Ceren Bakır Kösoğlu,
Süreyya Dede,
Emine Karakuş
et al.
Abstract:Glycosaminoglycans (GAGs) serve as a biomarker for mucopolysaccharidoses disease. In this study, a novel fluorometric method was developed to measure total GAGs in urine. Graphene oxide (GO) and rhodamine B (RhB), a cationic fluorescent dye, were employed in the development of the method. RhB attaches to the GO surface via electrostatic attraction, leading to the quenching of its fluorescence upon the establishment of the RhB–GO complex. However, the presence of GAGs prompts a resurgence of intense fluorescenc… Show more
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