A novel Hemi-Body Irradiation technique using electron beams (HBIe−)

Delinikolas, Panagiotis; Patatoukas, George; Kouloulias, V.; Dilvoi, Maria; Plousi, Agapi; Efstathopoulos, Efstathios; Platoni, Kalliopi

doi:10.1016/j.ejmp.2017.12.022

Cited by 6 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[25][26][27][28] Following previous publications of our experience with the clinical use of electron beam therapy for cutaneous disorders and in particular with TSEB therapy in the management of MF, our study evaluates the effectiveness and toxicity of low dose scheme. [29][30][31] In our patient cohort of 14 patients we demonstrated treatment results similar with those from relevant literature. Although the CR rate was 21.4% the OR rate was 92.4% as 13 out of 14 patients showed clear benefit in skin disease burden.…”

Section: Toxicity Of Treatmentsupporting

confidence: 77%

Low dose total skin electron beam therapy for the management of T cell cutaneous lymphomas

Georgakopoulos

Papadavid

Platoni

et al. 2020

Dermatologic Therapy

Self Cite

View full text Add to dashboard Cite

Mycosis fungoides (MF) represent the most common type of primary cutaneous lymphomas. Total skin electron beam (TSEB) therapy to a total skin administered dose of 36 Gy represents a very effective treatment regimen and its role in the management of MF is well established. Unfortunately, the issue in MF is that despite the proved effectiveness of radiation therapy, disease regress, and the main goal of TSEB treatment seems to be the prolongation of the overall response duration time. Taking into consideration the high radio‐sensitivity of the disease, lower radiation doses have been tested with acceptable and comparable results. We prospectively analyzed low dose TSEB in 14 patients treated at ATTIKON University Hospital from 2011 to 2017. After a median duration of follow up time of 39 months we found that low dose TSEB is an effective treatment option, since therapeutic results are more than acceptable, with minimal toxicity. The fact that it can be repeated safely in the natural course of a “regressive” disease makes it more attractive than the standard full dose scheme of 36 Gy.

show abstract

Section: Toxicity Of Treatmentsupporting

confidence: 77%

Low dose total skin electron beam therapy for the management of T cell cutaneous lymphomas

Georgakopoulos

Papadavid

Platoni

et al. 2020

Dermatologic Therapy

Self Cite

View full text Add to dashboard Cite

show abstract

“…Following previous publications reporting on clinical applications of TSEB, our study also evaluated the effectiveness and toxicity of low dose scheme compared to the standard dose of 36 Gy [26] , [27] , [28] . Even with the very small cohort of 14 patients we demonstrated that the overall response rate for both treatment schedules was excellent (93%).…”

Section: Discussionmentioning

confidence: 99%

Clinical application of Total Skin Electron Beam (TSEB) therapy for the management of T cell cutaneous lymphomas. The evolving role of low dose (12 Gy) treatment schedule

Georgakopoulos

Papadavid

Platoni

et al. 2019

Clinical and Translational Radiation Oncology

Self Cite

View full text Add to dashboard Cite

show abstract

“…The upper, middle or, lower half of the skeleton may be irradiated. Both photon beams and electron beams may be used [54,55]. Delivering 6–8 Gy in single fraction results in pain response in 70% of patients after 24–48 h [54].…”

Section: Painful Bone Metastasesmentioning

confidence: 99%

“…Delivering 6–8 Gy in single fraction results in pain response in 70% of patients after 24–48 h [54]. The intensity of pain is reduced significantly, from 8 to 1, according to the visual-analogue scale, and there is a decrease in morphine consumption [54,55]. It is a very convenient treatment type for advanced cancer patients since it involves a short hospital stay and acceptable side effects [54].…”

Section: Painful Bone Metastasesmentioning

confidence: 99%

Personalized Radiation Therapy in Cancer Pain Management

Sierko

Hempel

Zuzda

et al. 2019

Cancers

View full text Add to dashboard Cite

The majority of advanced cancer patients suffer from pain, which severely deteriorates their quality of life. Apart from analgesics, bisphosphonates, and invasive methods of analgesic treatment (e.g., intraspinal and epidural analgesics or neurolytic blockades), radiation therapy plays an important role in pain alleviation. It is delivered to a growing primary tumour, lymph nodes, or distant metastatic sites, producing pain of various intensity. Currently, different regiments of radiation therapy methods and techniques and various radiation dose fractionations are incorporated into the clinical practice. These include palliative radiation therapy, conventional external beam radiation therapy, as well as modern techniques of intensity modulated radiation therapy, volumetrically modulated arch therapy, stereotactic radiosurgery or stereotactic body radiation therapy, and brachytherapy or radionuclide treatment (e.g., radium-223, strontium-89 for multiple painful osseous metastases). The review describes the possibilities and effectiveness of individual patient-tailored conventional and innovative radiation therapy approaches aiming at pain relief in cancer patients.

show abstract

A novel Hemi-Body Irradiation technique using electron beams (HBIe−)

Abstract: In conclusion, HBIe was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.

Cited by 6 publications

References 21 publications

Low dose total skin electron beam therapy for the management of T cell cutaneous lymphomas

Low dose total skin electron beam therapy for the management of T cell cutaneous lymphomas

Clinical application of Total Skin Electron Beam (TSEB) therapy for the management of T cell cutaneous lymphomas. The evolving role of low dose (12 Gy) treatment schedule

Personalized Radiation Therapy in Cancer Pain Management

Contact Info

Product

Resources

About

A novel Hemi-Body Irradiation technique using electron beams (HBIe−)

Abstract: In conclusion, HBIe was proven effective in delivering the prescribed dose to the target area, while protecting the healthy skin.

Cited by 6 publications

References 21 publications

Low dose total skin electron beam therapy for the management of T cell cutaneous lymphomas

Low dose total skin electron beam therapy for the management of T cell cutaneous lymphomas

Clinical application of Total Skin Electron Beam (TSEB) therapy for the management of T cell cutaneous lymphomas. The evolving role of low dose (12 Gy) treatment schedule

Personalized Radiation Therapy in Cancer Pain Management

Contact Info

Product

Resources

About

Clinical application of Total Skin Electron Beam (TSEB) therapy for the management of T cell cutaneous lymphomas. The evolving role of low dose (12 Gy) treatment schedule