A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method

Single-domain antibodies as therapeutics for solid tumor treatment

“…It is well suited for high-throughput identification of antigen-specific clones with the help of different microarray-based methods such as micro-engraving and cell-based microarray chip systems 49 , 50 . Recently, with the rapid development in structure biology and the emergence of increasing numbers of protein-structure data, computational-based antibody humanization methods by homology modeling or artificial intelligence (AI) have also been designed for the generation of humanized or even fully human antibodies 51 , 52 .…”