A Novel Image Analysis of Light Emitting Diode Array Biostimulation Applied on Microcirculation

Su, Chuan-Tsung; Shan, Yi-Chia; Fang, Wei; Lin, Chii‐Wann; Juan, Ju-Hsuan; Lu, Kuan‐Ting; Wu, Jih‐Huah

doi:10.1109/ic3.2018.00034

Cited by 1 publication

(2 citation statements)

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“…The results showed a significant increase in blood flow in the treated group of both diabetic and non-diabetic patients (p = 0.040 and p = 0.033). Our previous study also found that the palm with 660 nm LED radiated can increased the velocity of erythrocytes in the nailfold capillary by approximately 1.7-fold [18]. In another study, a 20% increase in CBF was found in a patient in a permanent vegetative state who received an 850 nm LED on the left anterior frontal lobe [19].…”

Section: Introductionmentioning

confidence: 71%

“…PBM can be used for microcirculation improvement and increased diameter of arterial, venous, and lymphatic vessels [13][14]. The vessel diameter and blood flow of tissues following PBM have been examined [15][16][17][18][19][20][21]. Ihsan demonstrated that the 904 nm laser may enhance adenosine, growth hormone, fibroblast growth factor, fiber/capillary ratio, and capillary diameter in rabbits, therefore accelerating collateral circulation and improving microcirculation [15].…”

Section: Introductionmentioning

confidence: 99%

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Assessment of the Microcirculation in Superficial and Deep Biotissue with Photobiomodulation

2023

JEMOA

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Background Quantitative measurement of blood flow in specific biotissue targets is crucial for photobiomodulation therapy (PBMT). PBMT has been applied on many clinical applications. However, the conclusive confirmation of its effects on microcirculation and laser wavelength dependency in superficial and deep tissues is lacking. Objective This study examines the microcirculatory response and laser wavelength dependency of red and near infrared (NIR) lasers in biotissue. Laser Doppler flowmetry (LDF) was used to assess the flux and velocity of erythrocytes in buccal tissue when exposed to 660 nm and 830 nm laser radiation. Discussion The microcirculatory response of subjects during and after laser radiation were analyzed. Each laser has an energy density of 73.17 J/cm2 . Both the 660 nm and 830 nm lasers demonstrated the capability to enhance microcirculation in both superficial and deep tissues. Furthermore, we observed that laser wavelengths at 660 nm and 830 nm respectively enhanced the microcirculatory response in superficial and deep tissues. Importantly, this cumulative effect persisted for at least 10 minutes. Conclusions The present results indicate that PBM can effectively improve local blood perfusion in specific target areas and peripheral biotissues. These findings have potential applications in enhancing wound healing and local microcirculation within the target areas.

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Section: Introductionmentioning

confidence: 71%