A novel initial wiring technique for chronic total occlusion of the superficial femoral artery using the structural features of a polymer jacket guidewire

Abstract

Background: To evaluate the efficacy of the GLadIus MG drilLINg technique (GLIMGLIN), a novel initial wiring technique using the Gladius MGTM structural features, for crossing the superficial femoral artery (SFA) with chronic total occlusion (CTO). Methods: This retrospective, single-center study enrolled 27 symptomatic patients (mean age 77.4±8.5 years; 20 men) with de novo SFA CTO (mean CTO length 16.1±8.9 cm) who underwent GLIMGLIN as the initial wiring between January 2020 and December 2021. The success of GLIMGLIN was defined when the wire crossing was completed using a Gladius MGTM and a microcatheter without any additional devices. GLIMGLIN was defined as one of the conventional wiring techniques.Results: The success rates of GLIMGLIN and conventional wiring were 48.1% and 74.1%, respectively. Intravascular ultrasound findings showed complete true lumen passage in the GLIMGLIN success group. Compared to the failure group, the proximal (6.3±0.8 vs. 5.5±0.9 mm, p=0.02) and distal (5.9±0.5 vs. 5.4±0.6 mm, p=0.02) reference vessel diameters were significantly larger, and the rate of calcium angle >180° was significantly fewer (30.8 vs. 71.4 %, p=0.04) in the success group. No significant difference was shown in the CTO length between the group. Total wiring time, total procedure time, and fluoroscopic time were significantly shorter in the success group. Conclusions: GLIMGLIN may enable operators to perform CTO wiring easily, efficiently, and at a lower cost in selected cases.