2022
DOI: 10.1002/elan.202100506
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A Novel Label‐free Chronoamperometric Immunosensor Based on a Biocomposite Material for Rapid Detection of Carcinoembryonic Antigen

Abstract: In this research, poly(diallyldimethylammonium chloride)‐capped gold nanoparticles, nickel ferrite particles, and carbon nanotubes were combined to form a PANC metal composite. The prepared metal composite modified onto a glassy carbon electrode was electropolymerized with poly(o‐phenylenediamine) and immobilized with horseradish peroxidase, anti‐carcinoembryonic antigen antibody, and bovine serum albumin to create the label‐free immunosensors for rapid detection of carcinoembryonic antigen (CEA) using chronoa… Show more

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Cited by 6 publications
(1 citation statement)
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“…Poly(o-phenylenediamine)/carbon-coated nickel nanoparticles, modified with BSA, were prepared as glassy carbon electrodes, which can be used to detect and monitor bovine serum albumin and papaverine [18]. A glassy carbon electrode with immobilized horseradish peroxidase, anti-carcinoembryonic antigen antibodies, and bovine serum albumin was created with label-free immunosensors for the rapid detection of the carcinoembryonic antigen (CEA) using chronoamperometry, which was electropolymerized with poly(ophenylenediamine) and modified by PANC metal composite [19]. Bu's group introduced a self-assembled bienzymatic electrochemical biosensor, in which acetylcholinesterase (AChE) and choline oxidase were immobilized on a poly(o-phenylenediamine)-modified Au electrode [20].…”
Section: Introductionmentioning
confidence: 99%
“…Poly(o-phenylenediamine)/carbon-coated nickel nanoparticles, modified with BSA, were prepared as glassy carbon electrodes, which can be used to detect and monitor bovine serum albumin and papaverine [18]. A glassy carbon electrode with immobilized horseradish peroxidase, anti-carcinoembryonic antigen antibodies, and bovine serum albumin was created with label-free immunosensors for the rapid detection of the carcinoembryonic antigen (CEA) using chronoamperometry, which was electropolymerized with poly(ophenylenediamine) and modified by PANC metal composite [19]. Bu's group introduced a self-assembled bienzymatic electrochemical biosensor, in which acetylcholinesterase (AChE) and choline oxidase were immobilized on a poly(o-phenylenediamine)-modified Au electrode [20].…”
Section: Introductionmentioning
confidence: 99%