A novel medically imageable intelligent cellulose nanofibril-based injectable hydrogel for the chemo-photothermal therapy of tumors

Chen, Zhiping; Chen, Rimei; Zhao, Chao; Quan, Zongyan; Zhu, Hongxiang; Wang, Lei; Bu, Qing; He, Yonghui; He, Hui

doi:10.1016/j.cej.2021.133255

Cited by 24 publications

(12 citation statements)

References 41 publications

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“…In addition, the modified nanohydrogel can also achieve on-demand drug release through light response, magnetic response, ultrasonic response, electrical response, pH response, ROS response, enzyme response and MMPs response [ 226 – 229 ]. Furthermore, some nanomaterials can give hydrogels luminescence and imaging functions to better monitor drug release behavior [ 230 , 231 ]. For example, Zhu et al [ 232 ] developed an injectable MMPs- and ROS-responsive hydrogel.…”

Section: Discussionmentioning

confidence: 99%

Review targeted drug delivery systems for norcantharidin in cancer therapy

et al. 2022

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Norcantharidin (NCTD) is a demethylated derivative of cantharidin (CTD), the main anticancer active ingredient isolated from traditional Chinese medicine Mylabris. NCTD has been approved by the State Food and Drug Administration for the treatment of various solid tumors, especially liver cancer. Although NCTD greatly reduces the toxicity of CTD, there is still a certain degree of urinary toxicity and organ toxicity, and the poor solubility, short half-life, fast metabolism, as well as high venous irritation and weak tumor targeting ability limit its widespread application in the clinic. To reduce its toxicity and improve its efficacy, design of targeted drug delivery systems based on biomaterials and nanomaterials is one of the most feasible strategies. Therefore, this review focused on the studies of targeted drug delivery systems combined with NCTD in recent years, including passive and active targeted drug delivery systems, and physicochemical targeted drug delivery systems for improving drug bioavailability and enhancing its efficacy, as well as increasing drug targeting ability and reducing its adverse effects. Graphical Abstract

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Section: Discussionmentioning

confidence: 99%

Review targeted drug delivery systems for norcantharidin in cancer therapy

et al. 2022

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“…Cellulose nanofibril Hydrogel Chemo-photothermal therapy [114] Antimicrobial cellulose Hydrogel Wound healing [115] Regenerative cellulose Hydrogel Drug delivery system [116] Bacterial cellulose Membrane Wound healing [117] Cellulose sheet Porous medium Scaffold [118] Deacetylated cellulose acetate Nanoparticle Wound healing [119] Carboxymethyl cellulose Nanoparticle Chemo-photothermal therapy [120] Cellulose nanofiber Porous medium Biosensor [121] Cellulose Porous medium Wound healing [122] Bacterial cellulose Porous medium Tissue engineering [123] Chitin-chitosan Chitin Nanoparticle Drug delivery system [124] Carboxymethyl chitin Porous medium Anti-tumor chemotherapy [125] Chitin nanowhisker Hydrogel Drug delivery system [126] Amorphous chitin Nanoparticle Drug delivery system [127] Chitin Hydrogel Drug delivery system [128] Chitosan/cefazolin coatings on Ti Membrane Drug delivery system [129] Carboxylated chitosan Porous medium Drug delivery system [130] Chondro-inductive chitosan Hydrogel Tissue engineering [131] Vanillin-bioglass-chitosan Porous medium Tissue engineering [132] Polycaprolactone (PCL)-chitosan Porous medium Tissue engineering [133] Hyaluronic acid Hyaluronic acid Hydrogel Chemotherapeutic drugs [134] Hyaluronic acid Membrane Transdermal drug delivery [135] Hyaluronic acid-functionalized halloysite nanotube Porous medium CD44-overexpressing cancer cells [136] Hyaluronic acid loaded with silica particle Porous medium Drug delivery system [137] Hyaluronic acid/poly vinyl alcohol Membrane Biosensor [138] Polydopamine/hyaluronic acid Membrane Biosensor [139] Polypyrrole-sulfonated graphene/hyaluronic acid Porous medium Biosensor [140] Hyaluronic acid/chitosan Hydrogel Wound healing [141] Hyaluronic acid bilayers Scaffold Osteochondral defect regeneration [142] Hyaluronic acid/chitosan Scaffold Cartilage tissue engineering [143]…”

Section: Cellulose and Derivativesmentioning

confidence: 99%

Polysaccharides for Medical Technology: Properties and Applications

Sukhavattanakul

Pisitsak

Ummartyotin

et al. 2022

Macromolecular Bioscience

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Over the past decade, the use of polysaccharides has gained tremendous attention in the field of medical technology. They have been applied in various sectors such as tissue engineering, drug delivery system, face mask, and bio‐sensing. This review article provides an overview and background of polysaccharides for biomedical uses. Different types of polysaccharides, for example, cellulose and its derivatives, chitin and chitosan, hyaluronic acid, alginate, and pectin are presented. They are fabricated in various forms such as hydrogels, nanoparticles, membranes, and as porous mediums. Successful development and improvement of polysaccharide‐based materials will effectively help users to enhance their quality of personal health, decrease cost, and eventually increase the quality of life with respect to sustainability.

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“…into recognizable electrical signals, which help the vigorous development of e-skin, medical diagnosis, so robotics and other modern electronics. [1][2][3][4][5][6][7][8][9][10] The ideal wearable sensor should have excellent comprehensive characteristics, including mechanical robustness, environmental stability, high sensitivity, self-adhesion and self-healing properties. As typical soand-wet materials with electrical conductivity and tunable properties, hydrogels are emerging as promising candidates for the next generation of sensor applications.…”

Section: Introductionmentioning

confidence: 99%