In this paper, the mechanism of programming operation considering the source-to-floating gate coupling ratio (SCR) in split-gate source-side injected flash memory has been discussed and experimentally demonstrated. The effects of SCR on the programming performance and cycling endurance have also been investigated in detail. The experimental results indicate that the cell with higher SCR possesses a higher programming speed. Under the same programming speed, the higher-SCR cell shows larger cycling endurance compared to lower-SCR cell.