A novel method of blind bedside placement of postpyloric tubes

Sun, Jianfang; Wang, Xiang; Yuan, Shuo

doi:10.1186/s13054-018-1986-0

Cited by 9 publications

(15 citation statements)

References 3 publications

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“…Before EN began, a nasogastric or nasojejunal feeding tube (size 10F, Flocare, Nutricia Ltd) was placed as needed. The nasojejunal tube was inserted using our novel method of blind bedside post-pyloric placement[15]. In the EEN group, enteral feeding was initiated within the first 24-48 h, whereas in the DEN group, enteral feeding was initiated on the 4th day after admission.…”

Section: Methodsmentioning

confidence: 99%

Effects of early enteral nutrition on Th17/Treg cells and IL-23/IL-17 in septic patients

Sun

Zhang

Chen

et al. 2019

WJG

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BACKGROUND The imbalance of Th17/Treg cells and the IL-23/IL-17 axis have been confirmed to be associated with sepsis and various inflammatory diseases. Early enteral nutrition (EEN) can modulate the inflammatory response, improve immune dysfunction, and prevent enterogenic infection in critically ill patients; however, the precise mechanisms remain unclear. Considering the important roles of Th17 and Treg lymphocytes in the development of inflammatory and infectious diseases, we hypothesized that EEN could improve the immune dysfunction in sepsis by maintaining a balanced Th17/Treg cell ratio and by regulating the IL-23/IL-17 axis. AIM To investigate the effects of EEN on the Th17/Treg cell ratios and the IL-23/IL-17 axis in septic patients. METHODS In this prospective clinical trial, patients were randomly divided into an EEN or delayed enteral nutrition (DEN) group. Enteral feeding was started within 48 h in the EEN group, whereas enteral feeding was started on the 4th day in the DEN group. The Th17 and Treg cell percentages and the interleukin levels were tested on days 1, 3, and 7 after admission. The clinical severity and outcome variables were also recorded. RESULTS Fifty-three patients were enrolled in this trial from October 2017 to June 2018. The Th17 cell percentages, Th17/Treg cell ratios, IL-17, IL-23, and IL-6 levels of the EEN group were lower than those of the DEN group on the 7th day after admission ( P < 0.05). The duration of mechanical ventilation and of the intensive care unit stay of the EEN group were shorter than those of the DEN group ( P < 0.05). However, no difference in the 28-d mortality was found between the two groups ( P = 0.728). CONCLUSION EEN could regulate the imbalance of Th17/Treg cell ratios and suppress the IL-23/IL-17 axis during sepsis. Moreover, EEN could reduce the clinical severity of sepsis but did not reduce the 28-d mortality of septic patients.

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Section: Methodsmentioning

confidence: 99%

Effects of early enteral nutrition on Th17/Treg cells and IL-23/IL-17 in septic patients

Sun

Zhang

Chen

et al. 2019

WJG

Self Cite

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“…Some NIT placement methods also utilize the impact of the body position on the success rate of catheterization; these only involve the right lateral position. 29 The purpose of the right lateral position is to enable the NIT to enter the pylorus, which is located on the right side of the stomach body, through gravity. This differs from the direct placement achieved by the modified method.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of a modified method for blind bedside placement of post-pyloric feeding tube: a prospective preliminary clinical trial

et al. 2021

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Objective To compare the efficacy and safety of a new modified method of bedside post-pyloric feeding tube catheterization with the Corpak protocol versus electromagnetic-guided catheterization. Materials and Methods We conducted a single-center, single-blinded, prospective clinical trial. Sixty-three patients were treated with a non-gravity type gastrointestinal feeding tube using different procedures: modified bedside post-pyloric feeding tube placement (M group), the conventional Corpak protocol (C group), and standard electromagnetic-guided tube placement (EM group). Results The success rate in the M group, C group, and EM group was 82.9% (34/41), 70.7% (29/41), and 88.2% (15/17), respectively, with significant differences among the groups. The time required to pass the pylorus was significantly shorter in the M group (26.9 minutes) than in the C group (31.9 minutes) and EM group (42.1 minutes). The proportion of pylorus-passing operations completed within 30 minutes was significantly higher in the M group than in the C group and EM group. No severe complications occurred. Conclusion This modified method of bedside post-pyloric feeding tube catheterization significantly shortened the time required to pass the pylorus with no severe adverse reactions. This method is effective and safe for enteral nutrition catheterization of patients with dysphagia and a high risk of aspiration pneumonia.

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“…1a) was used in our isolation unit. The procedure of placement was similar to the method reported by our previous study [3,4]. Patients were placed in right decubitus position about 30-45°with bed head raised at about 30°.…”

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confidence: 99%

Practice of novel method of bedside postpyloric tube placement in patients with coronavirus disease 2019

et al. 2020

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A novel method of blind bedside placement of postpyloric tubes

Cited by 9 publications

References 3 publications

Effects of early enteral nutrition on Th17/Treg cells and IL-23/IL-17 in septic patients

Effects of early enteral nutrition on Th17/Treg cells and IL-23/IL-17 in septic patients

Efficacy and safety of a modified method for blind bedside placement of post-pyloric feeding tube: a prospective preliminary clinical trial

Practice of novel method of bedside postpyloric tube placement in patients with coronavirus disease 2019

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