A novel metronidazole fluorescent nanosensor based on graphene quantum dots embedded silica molecularly imprinted polymer

Mehrzad-Samarin, Mina; Faridbod, Farnoush; Dezfuli, Amin Shiralizadeh; Ganjali, Mohammad Reza

doi:10.1016/j.bios.2016.10.047

Cited by 161 publications

(63 citation statements)

References 19 publications

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“…Graphene quantum dots (GQDs) are a new class of carbon nanomaterial, which have lower toxicity and better biocompatibility than the traditional QDs [ 23 , 24 ]. GQDs have been directly used to detect cytochrome c [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Nanosensor Based on Molecularly Imprinted Polymers Coated on Graphene Quantum Dots for Fast Detection of Antibiotics

2018

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In this work, we developed a novel fluorescent sensor by combining molecularly imprinted polymers (MIPs) with graphene quantum dots (GQDs) for the determination of tetracycline (TC) in aqueous samples. Firstly, we developed a one-pot green method to synthesize GQDs as the fluorescent probes. GQDs with carboxyl groups or amino groups were fabricated. It was found that carboxyl groups played an important role in the fluorescence quenching. Based on these findings, the GQDs-MIPs microspheres were prepared using a sol-gel process. GQDs-MIPs showed strong fluorescent emission at 410 nm when excited at 360 nm, and the fluorescence was quenched in the presence of TC. Under optimum conditions, the fluorescence intensity of GQDs-MIPs decreased in response to the increase of TC concentration. The linear rage was from 1.0 to 104 µg·L−1, and the limit of detection was determined to be 1 µg·L−1. The GQDs-MIPs also demonstrated high selectivity towards TC. The fluorescent sensor was successfully applied for the detection of TC in real spiked milk samples.

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Section: Introductionmentioning

confidence: 99%

Fluorescent Nanosensor Based on Molecularly Imprinted Polymers Coated on Graphene Quantum Dots for Fast Detection of Antibiotics

2018

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“…Several quantitative analytical methods have been reported to detect the concentration of MNZ in different matrices, such as ultraviolet spectrophotometry, 11,12 uorescence spectroscopy, 13,14 gas chromatography, 15 high-performance liquid chromatography, 16 immunoassay, 17 solid phase extraction, 18 electrochemical sensor. [19][20][21] However, spectrophotometric methods have some drawbacks such as requirement of long time heating, the use of nonaqueous systems, narrow range of determination, stability of the colored product formed, etc.…”

Section: Introductionmentioning

confidence: 99%

Carbon quantum dots as a fluorophore for “inner filter effect” detection of metronidazole in pharmaceutical preparations

et al. 2019

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“…In recent decades, graphene quantum dots (GQDs) films modified electrodes have been attracting great attentions due to their wide applications in the fields of electrochemical sensors . Because of remarkable advantages, such as low toxicity, easy preparation, high chemical stability, environmental friendliness, ability to transfer photo‐induced electron, and excellent photo‐stability, GQDs have been studied directly for electrochemical sensor applications …”

Section: Introductionmentioning

confidence: 99%

Electrochemical monitoring of aflatoxin M1 in milk samples using silver nanoparticles dispersed on α‐cyclodextrin‐GQDs nanocomposite

Shadjou

Hasanzadeh

Heidar-poor

et al. 2018

J of Molecular Recognition

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Aflatoxins are potential food pollutants produced by fungi. One of important toxins is aflatoxin M1 (AFM1). A great deal of concern is associated with AFM1 toxicity. In the present study, an innovative electrochemical interface for quantitation of AFM1 based on ternary signal amplification strategy was fabricated. In this work, silver nanoparticles was electrodeposited onto green and biocompatible nanocomposite containing α-cyclodextrin as conductive matrix and graphene quantum dots as amplification element. Therefore, a multilayer film based on α-cyclodextrin, graphene quantum dots, and silver nanoparticles was exploited to develop a highly sensitive electrochemical sensor for detection of AFM1. Fully electrochemical methodology was used to prepare a transducer on a glassy carbon electrode, which provided a high surface area toward sensitive detection of AFM1. The surface morphology of electrode surface was characterized by high-resolution field emission scanning electron microscope. The proposed sensing platform provides a simple tool for AFM1 detection. Under optimized condition, the calibration curve for AFM1 concentration was linear in 0.015mM to 25mM with low limit of quantification of 2μM. The practical analytical utility of the modified electrode was illustrated by determination of AFM1 in unprocessed milk samples.

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A novel metronidazole fluorescent nanosensor based on graphene quantum dots embedded silica molecularly imprinted polymer

Cited by 161 publications

References 19 publications

Fluorescent Nanosensor Based on Molecularly Imprinted Polymers Coated on Graphene Quantum Dots for Fast Detection of Antibiotics

Fluorescent Nanosensor Based on Molecularly Imprinted Polymers Coated on Graphene Quantum Dots for Fast Detection of Antibiotics

Carbon quantum dots as a fluorophore for “inner filter effect” detection of metronidazole in pharmaceutical preparations

Electrochemical monitoring of aflatoxin M1 in milk samples using silver nanoparticles dispersed on α‐cyclodextrin‐GQDs nanocomposite

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