A novel mixed-mode solid phase extraction for simultaneous determination of melamine and cyanuric acid in food by hydrophilic interaction chromatography coupled to tandem mass chromatography

Deng, Xiaojun; Guo, Dehua; Zhao, Shanzhen; Han, Lijun; Sheng, Yunlong; Yi, Xionghai; Zhou, Yao; Peng, Tao

doi:10.1016/j.jchromb.2010.08.038

Cited by 34 publications

(14 citation statements)

References 15 publications

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“…Since MEL-contaminated milk powder and other foods manufactured in China and USA in 2008 were reported, which resulted in kidney damage, renal failure and even the death of infants and pets 24,25 , the detection of MEL has drawn much international attention. Various analytical methods have been used in the determination of MEL in dairy products such as high performance liquid chromatography (HPLC)-UV detection (HPLC-UV) [26][27][28] or -tandem mass spectrometry (LC-MS/MS) [29][30][31] . And the hydrophilic interaction liquid chromatography (HILIC) 32 , surface-enhanced Raman spectroscopy (SERS) 33 and surface plasmon resonance (SPR) 34 suspension with the protection of N 2 flow and stirred for min.…”

Section: Analytical Sciencesmentioning

confidence: 99%

A High-matched Melamine Sensor Using Core/shell Nano Particles of Fe3O4@Polyrutin–COOH and Ionic Liquid as Imprinted Polymeric Monomers

2020

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Herein, a magnetic molecular imprinted polymeric ionic liquid (MMIPIL) film was designed by using the functionalized ionic liquid (3-vinyl-4-amino-5imidazole carboxamide chloride, IL) and Fe 3 O 4 @Polyrutin-COOH as functional monomer and supporting materials. The change in the direction of the charge density in the structure of MMIPIL polymer resulted in a red shift about 100nm for the characteristic group of-C=O. Polyrutin containing electron-rich benzene ring and multiple hydroxyl groups not only prevented the aggregation of Fe 3 O 4 , but also benefitted to immobilize template molecules. The more symmetric amino groups in template molecules generated more hydrogen bonds and other synergistic effects between MEL and functional monomers, which resulted in a high-matched and high stable MMIPIL sensor. The proposed magnetic sensor lowered the matching potential, and enhanced the signal for the detection of melamine (MEL) in milk powder. Under the optimum conditions, the MEL template molecule showed a significant linear relationship between 5.0×10-3 and 0.8 µg/L with a detection limit (S / N = 3) of 1.5× 10-3 µg/L. The MMIPIL sensor showed wonderful selectivity and exhibited facile, fast and efficient results in the monitoring MEL with the recoveries between 96.5% and 108.3%.

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Section: Analytical Sciencesmentioning

confidence: 99%

A High-matched Melamine Sensor Using Core/shell Nano Particles of Fe3O4@Polyrutin–COOH and Ionic Liquid as Imprinted Polymeric Monomers

2020

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“…There are at least several mechanisms: cation exchange interaction, hydrophilic interaction, hydrogen bonding, and target‐specific recognition (e.g., by molecularly imprinted materials). Cation exchange interaction was regarded to be the main mechanism for MEL retention on the commercially available sorbents and attapulgite nanoparticles . The molecularly imprinted materials, including MIPs, molecularly imprinted layer‐coated microspheres/films/magnetic particles, were prepared with MEL and/or its analogs as template(s), showing specific recognition for these compounds.…”

Section: Mechanismsmentioning

confidence: 99%

“…According to the studies mentioned above, many kinds of materials, including commercially available sorbents [18][19][20][21][22][23], molecularly imprinted materials [24][25][26][27][28][29][30][31][32][34][35][36][37][38], strongcation-exchange restricted access materials [39], ampholinefunctionalized hybrid organic-inorganic silica materials [40] and activated attapulgites [42] can be employed for extracting MEL and its analogs from various matrices. The molecularly imprinted materials play a significant role in MEL and its analogs analysis because they have own unique characteristics, such as its recognition ability.…”

Section: Other Spe-based Materialsmentioning

confidence: 99%

Analysis of melamine and analogs in complex matrices: Advances and trends

Wang

Chen

et al. 2016

J of Separation Science

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The analysis of melamine and its analogs is of increasing research interest. Owing to their high nitrogen content and low price, they were deliberately added to artificially enhance protein concentration in a number of different types of human and animal food sources. In addition, environmental water might also be contaminated by melamine due to its use in the chemical industry and the degradation of the pesticide cyromazine. Herein we provide a detailed overview of recently developed materials and techniques for the analysis of melamine and its analogs in complex matrices, especially in dairy products (e.g., milk and powdered milk) and environmental water.

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“…Compared with other classical sample‐preparation techniques, SPE is a prevalent approach due to its high recovery, rapid phase separation, low cost, and low consumption of organic solvents. Many kinds of SPE sorbents have been commercially available for the extraction of melamine so far, such as silica gel, LiChroprep® RP‐2 powder, and cation exchange sorbent . Nevertheless, single‐interaction mechanism is normally insufficient to extract melamine and remove impurities in complex samples.…”

Section: Introductionmentioning

confidence: 99%

Hydrophilic solid-phase extraction of melamine with ampholine-modified hybrid organic-inorganic silica material

Wang

Zhu

et al. 2014

J. Sep. Science

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In this work, an ampholine-functionalized hybrid organic-inorganic silica sorbent was successfully used to extract melamine from a milk formula sample by a hydrophilic interaction solid-phase extraction protocol. Primary factors affecting the extraction efficiency of the material such as extraction solvent, elution solvent, sample loading volume, and elution volume have been thoroughly optimized. Under the optimized hydrophilic solid-phase extraction conditions, the recoveries of melamine spiked in milk formula samples ranged from 86.2 to 101.8% with relative standard deviations of 4.1-9.4% (n = 3). The limit of detection (S/N = 3) was 0.32 μg/g. The adsorption capacity toward melamine was 30 μg of melamine per grams of sorbent. Due to its simplicity, rapidity and cost effectiveness, the newly developed hydrophilic solid-phase extraction method should provide a promising tool for daily monitoring of doped melamine in milk formula.

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A novel mixed-mode solid phase extraction for simultaneous determination of melamine and cyanuric acid in food by hydrophilic interaction chromatography coupled to tandem mass chromatography

Cited by 34 publications

References 15 publications

A High-matched Melamine Sensor Using Core/shell Nano Particles of Fe3O4@Polyrutin–COOH and Ionic Liquid as Imprinted Polymeric Monomers

A High-matched Melamine Sensor Using Core/shell Nano Particles of Fe3O4@Polyrutin–COOH and Ionic Liquid as Imprinted Polymeric Monomers

Analysis of melamine and analogs in complex matrices: Advances and trends

Hydrophilic solid-phase extraction of melamine with ampholine-modified hybrid organic-inorganic silica material

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