is research presents a novel hybrid prediction technique, namely, self-tuning least squares support vector machine (ST-LSSVM), to accurately model the friction capacity of driven piles in cohesive soil.e hybrid approach uses LS-SVM as a supervised-learning-based predictor to build an accurate input-output relationship of the dataset and SOS method to optimize the σ and c parameters of the LS-SVM. Evaluation and investigation of the ST-LSSVM were conducted on 45 training data and 20 testing data of driven pile load tests that were compiled from previous studies. e prediction accuracy of the ST-LSSVM was then compared to other machine learning methods, namely, LS-SVM and BPNN, and was benchmarked with the previous results by neural network (NN) from Goh using coefficient of correlation (R), mean absolute error (MAE), and root mean square error (RMSE). e comparison showed that the ST-LSSVM performed better than LS-SVM, BPNN, and NN in terms of R, RMSE, and MAE. is comprehensive evaluation confirmed the capability of hybrid approach SOS and LS-SVM to modeling the accurate friction capacity of driven piles in clay. It makes for a reliable and robust assistance tool in helping all geotechnical engineers estimate friction pile capacity.