2015
DOI: 10.1016/j.jbiomech.2015.04.032
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A novel non-invasive ultrasonic method to assess total axial stress of the common carotid artery wall in healthy and atherosclerotic men

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Cited by 14 publications
(11 citation statements)
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“…A similar hypothesis was formulated in a study that evaluated the association of LOKI with both left ventricular cardiac motion and local blood velocity . A strong association between LOKI and the severity of carotid stenosis was demonstrated, potentially constituting a tool to screen arterial sites known to be predisposed to atherosclerotic plaque formation . In addition to motion amplitude, two new indices of arterial stiffness derived from LOKI waveforms were explored: the total distance of the intima trajectory during one heart cycle, as well as the degree of a polynomial function fitting LOKI, were found to be associated with arterial stiffness measurements .…”
Section: Introductionmentioning
confidence: 85%
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“…A similar hypothesis was formulated in a study that evaluated the association of LOKI with both left ventricular cardiac motion and local blood velocity . A strong association between LOKI and the severity of carotid stenosis was demonstrated, potentially constituting a tool to screen arterial sites known to be predisposed to atherosclerotic plaque formation . In addition to motion amplitude, two new indices of arterial stiffness derived from LOKI waveforms were explored: the total distance of the intima trajectory during one heart cycle, as well as the degree of a polynomial function fitting LOKI, were found to be associated with arterial stiffness measurements .…”
Section: Introductionmentioning
confidence: 85%
“…10 A strong association between LOKI and the severity of carotid stenosis was demonstrated, potentially constituting a tool to screen arterial sites known to be predisposed to atherosclerotic plaque formation. 11 In addition to motion amplitude, two new indices of arterial stiffness derived from LOKI waveforms were explored: the total distance of the intima trajectory during one heart cycle, as well as the degree of a polynomial function fitting LOKI, were found to be associated with arterial stiffness measurements. 12 It was further demonstrated that LOKI is inversely associated with arterial stiffening, 13 and that LOKI provides complementary information regarding arteriosclerosis and risk factors compared to traditional markers.…”
Section: Introductionmentioning
confidence: 99%
“…After at least 10 minutes of rest in the supine position, the ultrasonographic examination of the common carotid artery that received a greater radiation dose during treatment, 2-3 cm beneath the bifurcation region, was carried out as described in a previous study [ 17 ]. The SSI-6000 model of the Sonoscape ultrasonography system (SSI-6000 model, Shenzhen, China) equipped with a 6-11 MHz linear transducer was employed.…”
Section: Methodsmentioning
confidence: 99%
“…The outer layer—the adventitia—shows the same basic pattern of movement, but the displacement is smaller, thereby demonstrating the presence of previously unknown substantial shear strain and thus shear stress, intramurally [ 13 , 23 , 33 , 46 ]. Recent studies have reported that the amplitude of the longitudinal displacement of the arterial wall is reduced in patients with carotid plaques, suspected coronary artery disease, type 2 diabetes [ 38 40 , 42 , 45 ], and periodontal disease [ 47 ], suggesting that the longitudinal movement of the arterial wall might prove to be a valuable marker for future risk of cardiovascular disease. Furthermore, in a study on the porcine carotid artery, we recently reported that longitudinal movement and intramural shear strain undergo profound changes in response to the important endogenous hormones adrenalin and noradrenalin [ 2 ].…”
Section: Introductionmentioning
confidence: 99%