A novel nonplanar fused pentacycle dual-state emission (DSE) fluorophore

Constructing Dual-State Emissive Fluorophores via Boc Protection and Discovering a High-Fidelity Imaging Probe for Lipid Droplets

“…In contrast, dual-state emissive (DSE) fluorophores can exhibit strong fluorescence in both solution and solids, filling the gap between ACQ fluorophores and AIE fluorophores. Since it was first reported by Tang’s group in 2015, DSE fluorophores have attracted great attention, due to their broad application prospects. − However, the creation of DSE fluorophores is currently a fascinating challenge due to the lack of effective and universal methods. − So far, most DSE fluorophores are built on twisting molecular scaffolds, such as tetraphenylethylenes (TPE), triphenylamines (TPA), and other AIE molecular blocks. − Additionally, most of the reported DSE fluorophores exhibit short wavelength blue to yellow fluorescence, − which limits their application ranges, such as fluorescence imaging in biological systems . Therefore, it is a meaningful task to develop a simple and effective universal method to design and develop novel DSE fluorophores, especially with long wavelength emissions.…”