A Novel Photonic Crystal BioNEMS Sensing Platform Based on Fano resonances

Marvi, Fahimeh; Jafari, Kian

doi:10.1109/jlt.2021.3110254

Cited by 9 publications

(5 citation statements)

References 33 publications

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“…As summarized in table 2, the proposed BioNEMS sensor overcomes the topology represented in [44] in terms of all reported functional characteristics. In addition, the detection sensitivity of the proposed BioNEMS sensor is much larger than those reported in [38,43]. About the Q-factor and the FOM, although these functional characteristics in the proposed biosensor are smaller than those of the device proposed in [38], these parameters are comparable to those obtained in [43].…”

Section: Comparative Studymentioning

confidence: 59%

“…In addition, the detection sensitivity of the proposed BioNEMS sensor is much larger than those reported in [38,43]. About the Q-factor and the FOM, although these functional characteristics in the proposed biosensor are smaller than those of the device proposed in [38], these parameters are comparable to those obtained in [43]. As a result, the presented metamaterial BioNEMS sensor can provide an appropriate overall performance for biosensing applications and is appealing for highly sensitive and precise diagnoses of various types of diseases and their progress level in POC applications, according to the obtained functional characteristics.…”

Section: Comparative Studymentioning

confidence: 79%

“…Recently, several important contributions have been proposed in the related field [38,43,44]. In their proposed topologies, the detection mechanism is based on the wavelength modulation where the different concentrations of the biological quantities are directly sensed by RI changes.…”

Section: Comparative Studymentioning

confidence: 99%

“…Various types of optical detection mechanisms (such as plasmonics [29][30][31], metamaterials [32][33][34][35][36][37] and photonic devices [7,38]) have been addressed during the last years for different applications.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A label-free biomarkers detection platform relied on a bilayer long-wave infrared metamaterials BioNEMS sensor

Marvi¹,

Jafari²

2022

Nanotechnology

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A novel approach based on optical BioNEMS (Biological-Nano-Electro-Mechanical-Systems) sensor is presented in this paper to provide highly sensitive and precise detection of biomolecules. The proposed BioNEMS sensor is relied on a bi-layer metamaterials structure, tuned by its wavelength. The presented biosensor consists of a BioNEMS membrane coated by complementary split ring resonators (CSRRs) and an array of SRR cells on the substrate. While the immobilized bioreceptors adsorb the biomarkers (i.e. mRNA or protein), it causes a bending of the suspended membrane. This is due to the differential surface stress which is induced on the NEMS structure. As a consequence, the coupling strength of two complementary metamaterial layers and thus the electromagnetic response of the biosensor are changed. Furthermore, the proposed device is designed and analyzed by numerical and analytical approaches in order to obtain its functional characteristics as follows: detection sensitivity of 21967 nm/RIU, FOM of 327.8, mechanical sensitivity of 2.6 µm and resonant frequency of 4.92 kHz. According to the obtained results, the functional characteristics of the proposed label-free biosensor show its high potential for highly sensitive and accurate molecule detections, disease diagnosis as well as drug delivery tests for Lab-On-Chip systems.

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Section: Comparative Studymentioning

confidence: 59%

Section: Comparative Studymentioning

confidence: 79%

Section: Comparative Studymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A label-free biomarkers detection platform relied on a bilayer long-wave infrared metamaterials BioNEMS sensor

Marvi¹,

Jafari²

2022

Nanotechnology

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“…Monitoring the current changes of FET transistors implemented on cantilever surfaces or using a tunable surface stress-based membrane in a Fabry-Perot resonator have been proposed as alternatives to the conventional free-space laser method [116,117]. Moreover, novel designs of BioMEMS sensors can be promising choices in obtaining high-performance devices to facilitate the detection of very small changes in biological interactions without comprising specific features of a highresolution cavity [118].…”

Section: Biomems Sensorsmentioning

confidence: 99%

Alzheimer's Disease Diagnosis in the Preclinical Stage: Normal Aging or Dementia

Marvi,

Chen,

Sawan

2024

IEEE Rev. Biomed. Eng.

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Alzheimer's disease (AD) progressively impairs the memory and thinking skills of patients, resulting in a significant global economic and social burden each year. However, diagnosis of this neurodegenerative disorder can be challenging, particularly in the early stages of developing cognitive decline. Current clinical techniques are expensive, laborious, and invasive, which hinders comprehensive studies on Alzheimer's biomarkers and the development of efficient devices for Point-of-Care testing (POCT) applications. To address these limitations, researchers have been investigating various biosensing techniques. Unfortunately, these methods have not been commercialized due to several drawbacks, such as low efficiency, reproducibility, and the lack of accurate identification of AD markers. In this review, we present diverse promising hallmarks of Alzheimer's disease identified in various biofluids and body behaviors. Additionally, we thoroughly discuss different biosensing mechanisms and the associated challenges in disease diagnosis. In each context, we highlight the potential of realizing new biosensors to study various features of the disease, facilitating its early diagnosis in POCT. This comprehensive study, focusing on recent efforts for different aspects of the disease and representing promising opportunities, aims to conduct the future trend toward developing a new generation of compact multipurpose devices that can address the challenges in the early detection of AD.

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A proposal for an ultra-sensitive nano-displacement sensing system based on all-dielectric metamaterials with tunable ultra-sharp Fano resonance peaks

Karimipour,

Naeimi,

Javadifar

et al. 2023

Opt Quant Electron

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A Novel Photonic Crystal BioNEMS Sensing Platform Based on Fano resonances

Cited by 9 publications

References 33 publications

A label-free biomarkers detection platform relied on a bilayer long-wave infrared metamaterials BioNEMS sensor

A label-free biomarkers detection platform relied on a bilayer long-wave infrared metamaterials BioNEMS sensor

Alzheimer's Disease Diagnosis in the Preclinical Stage: Normal Aging or Dementia

A proposal for an ultra-sensitive nano-displacement sensing system based on all-dielectric metamaterials with tunable ultra-sharp Fano resonance peaks

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