A novel pillar-layered MOF with the urea linkers: A capable catalyst for the synthesis of new 1,8-naphthyridines via the anomeric-based oxidation

Abstract

Metal-based catalysts play an essential role in organic chemistry and the chemical industry. In this research, a pillar-layered metal-organic framework (MOF) with the urea linkers, namely Basu-HDI, as a novel and efficient heterogeneous catalyst was designed and successfully synthesized. Various techniques such as FT-IR, EDX, elemental mapping, SEM, XRD, BET, and TGA/DTA studied its structure and morphology. Then, we investigated the synthesis of new 1,8-naphthy-ridines utilizing Basu-HDI in mild conditions via a one‐pot three‐component tandem Knoevenagel/ Michael/cyclization/anomeric-based oxidation reaction. Final products were achieved by anomeric-based oxidation without employing an oxidation agent. Remarkably, this tandem process gave a good range of new 1,8-naphthyridines with high yields in a short reaction time. The pure products were confirmed by FT-IR, 1H NMR, 13C NMR, and mass spectrometry techniques. Moreover, the introduced catalyst showed good efficiency and stability and can be reused four times without significantly reducing efficiency.