A novel probe for identifying breast cancer cells based on fluorescence response of the cascade process of biothiol and viscosity

A fluorescent probe for imaging nitroreductase with signal amplification in high-viscosity environments

“…In addition to hypoxia, increased viscosity is an important characteristic of cancer cells. 18,19 Several research groups have developed fluorescent probes based on the cascade response of viscosity and other biomarkers including glutathione (GSH), 20 H 2 O 2 , 21 H 2 S, 22 and ONOO − 23 with exciting results. However, no such fluorescent probes for NTR have been reported.…”