A novel process for extraction of natural sweetener from licorice (Glycyrrhiza glabra) roots

Mukhopadhyay, Mausumi; Panja, Palash

doi:10.1016/j.seppur.2008.06.013

Cited by 100 publications

(49 citation statements)

References 12 publications

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“…Some authors have investigated the use of modifiers or additives to improve the extraction yields; for instance, Mukhopadhyay and Panja carried out the extraction of high amounts of natural sweeteners from licorice by SWE with 0.01 % w/v ammonia [137] and Arapitsas and Turner [138] developed a fast extraction method of anthocyanins from red cabbage using pressurized hot water containing 5 % of ethanol [138]. Other authors have studied how to extend the applicability of SWE to compounds exhibiting limited water solubility by pH control, thus Euterpio et al employed SWE for extracting curcumin from turmeric rhizomes by adjusting the water pH [139].…”

Section: Methodological and Technological Advancesmentioning

confidence: 99%

Compressed fluids for the extraction of bioactive compounds

Herrero

Castro-Puyana

Mendiola

et al. 2013

TrAC Trends in Analytical Chemistry

311

150

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ABSTRACT.The improvement of sample preparation and extraction techniques for natural bioactive compounds determinations is of great importance nowadays. New concepts are being introduced in this field, not only related to enhancement of extraction efficiencies but also related to environmental impact. This evolution towards Green Chemistry is pushing to new extraction and sample preparation processes that should be faster, more reproducible and more environmentally friendly. In this context, compressed fluidsbased sample preparation techniques (such as supercritical fluid extraction and pressurized liquid extraction) are demonstrating good capabilities. In this review, an updated knowledge on the techniques will be presented together with the main technical developments and the most notable recent applications for the extraction of bioactive compounds.Keywords: bioactive compounds, natural samples, plants, agricultural by-products, pressurized liquid extraction, supercritical fluid extraction, subcritical water extraction Abbreviations: ASE, accelerated solvent extraction; DHA, docosahexaenoic acid; EAE, enzyme-assisted extraction; EPA, eicosapentaenoic acid; IL, ionic liquids; MIP, molecular imprinted polymers; PFE, pressurized fluid extraction; PHSE, pressurized hot solvent extraction; PHWE, pressurized hot water extraction; PLE, pressurized liquid extraction; PLPW, pressurized low polarity water extraction; n-3 PUFA, n-3 polyunsaturated fatty acid; RAM, restricted access media; scCO2, supercritical CO2; SFE, supercritical fluid extraction; SHWE, superheated water extraction; SPE, solid Published in TrAC. Trends in analytical chemistry [0165-99362012 vol:43 pg:67 -83 http://dx.doi.org/10.1016/j.trac.2012.12.008 3 phase extraction; SWE, subcritical water extraction; TG, triglycerides; UAE, ultrasound assisted extraction; WEPO, water extraction and particle formation on-line.

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Section: Methodological and Technological Advancesmentioning

confidence: 99%

Compressed fluids for the extraction of bioactive compounds

Herrero

Castro-Puyana

Mendiola

et al. 2013

TrAC Trends in Analytical Chemistry

311

150

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“…Its dried roots, which are collected in autumn, are widely used (Eng et al 2007) in traditional medicine. The chemical constituents of the roots include several bioactive compounds, such as glycyrrhizin (~16 %), different sugars (up to 18 %), flavonoids, saponoids, sterols, starches, amino acids, gums and essential oils (Mukhopadhyay and Panja 2008). The main constituent found in the root is glycyrrhizin (Chen et al 1991).…”

Section: Introductionmentioning

confidence: 99%

Optimization of microwave assisted extraction (MAE) and soxhlet extraction of phenolic compound from licorice root

et al. 2014

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In present study, response surface methodology was used to optimize extraction condition of phenolic compounds from licorice root by microwave application. Investigated factors were solvent (ethanol 80 %, methanol 80 % and water), liquid/solid ratio (10:1-25:1) and time (2-6 min). Experiments were designed according to the central composite rotatable design. The results showed that extraction conditions had significant effect on the extraction yield of phenolic compounds and antioxidant capacities. Optimal condition in microwave assisted method were ethanol 80 % as solvent, extraction time of 5-6 min and liquid/solid ratio of 12.7/1. Results were compared with those obtained by soxhlet extraction. In soxhlet extraction, Optimum conditions were extraction time of 6 h for ethanol 80 % as solvent. Value of phenolic compounds and extraction yield of licorice root in microwave assisted (MAE), and soxhlet were 47.47 mg/g and 16.38 %, 41.709 mg/g and 14.49 %, respectively. These results implied that MAE was more efficient extracting method than soxhlet.

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“…Some reports demonstrated the antifungal activity of some botanical extracts such as Glycyrrhiza glabra (licorice), which grows in subtropical climates in Europe, Middle East and Western Asia (Reddy et al 2009;Nitalikar et al 2010). G. glabra (licorice) roots and rhizomes are extensively used in natural medicines for their biological properties (Mukhopadhyay and Panja 2008;Cho et al 2012). Moreover, documented clinical and experimental studies have demonstrated the anti-inflammatory, antioxidant and immunomodulatory effects of the licorice extract (Dhingra et al 2004;Dhingra and Sharma 2006;Cho et al 2012).…”

Section: Introductionmentioning

confidence: 99%

Antitoxin Characteristic of Licorice Extract: The Inhibitory Effect on Aflatoxin Production in Aspergillus parasiticus

Mohseni

Noorbakhsh

Moazeni

et al. 2014

Journal of Food Safety

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Recent investigations revealed the effects of herbal extracts on both fungal growth as well as aflatoxins production. In the present study, we tried to evaluate antifungal activity as well as antitoxin activity of Glycyrrhiza glabra (licorice) extract. Strain American Type Culture Collection 15517 of Aspergillus parasiticus was used to perform antifungal susceptibility test according to Clinical and Laboratory Standards Institute document M27-A3, and the rate of aflatoxin production was determined using high-performance liquid chromatography technique after exposure to different concentrations of licorice extract. Quantitative changes in the expression of the aflR gene were analyzed by measuring the cognate aflR mRNA level with quantitative real-time reverse-transcription polymerase chain reaction assay. Our obtained results demonstrated the inhibitory effect of licorice extract on Aspergillus parasiticus growth at 500 mg/mL of licorice extract. In addition, a significant decrease in aflatoxin production was revealed at the same concentration. However, the production of aflatoxin B1 was entirely inhibited in 10 g/mL of licorice extract. The level of aflR gene expression was significantly decreased after the exposure of fungal cells to 500 g/mL of licorice extract. Evaluation of the antifungal and antitoxin activity of licorice extract on Aspergillus parasiticus revealed its antifungal properties as well as its effective ability to decrease aflatoxin production.

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A novel process for extraction of natural sweetener from licorice (Glycyrrhiza glabra) roots

Cited by 100 publications

References 12 publications

Compressed fluids for the extraction of bioactive compounds

Compressed fluids for the extraction of bioactive compounds

Optimization of microwave assisted extraction (MAE) and soxhlet extraction of phenolic compound from licorice root

Antitoxin Characteristic of Licorice Extract: The Inhibitory Effect on Aflatoxin Production in Aspergillus parasiticus

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