A Novel Puncturable Atrial Septal Defect Occluder

Zhang, Xiaochun; Chen, Shasha; Li, Wei; Jilaihawi, Hasan; Piayda, Kerstin; Sievert, Horst; Zhou, Daxin; Pan, Wenzhi; Ge, Junbo

doi:10.1016/j.jacbts.2022.06.010

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…Although a novel puncturable ASD occluder (ReAces device) consisting of memory nickel-titanium wire and PET membrane has been recently introduced by Zhang X et al . [ 58 ], it is still in the research stage. Therefore, the evolution of biodegradable implants presents great advantage in the aspect of reducing device-associated short- or long-term complications.…”

Section: Introductionmentioning

confidence: 99%

Recent Development of Biodegradable Occlusion Devices for Intra-Atrial Shunts

Li,

Chen,

Xie

et al. 2024

Rev. Cardiovasc. Med.

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Atrial septal defect (ASD) is the third most common type of structural congenital heart defect. Patent foramen ovale (PFO) is an anatomical anomaly in up to 25% of the general population. With the innovation of occlusion devices and improvement of transcatheter techniques, percutaneous closure has become a first-line therapeutic alternative for treatment of ASD and PFO. During the past few decades, the development of biodegradable occlusion devices has become a promising direction for transcatheter closure of ASD/PFO due to their biodegradability and improved biocompatibility. The purpose of this review is to comprehensively summarize biodegradable ASD/PFO occlusion devices, regarding device design, materials, biodegradability, and evaluation of animal or clinical experiments (if available). The current challenges and the research direction for the development of biodegradable occluders for congenital heart defects are also discussed.

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Section: Introductionmentioning

confidence: 99%

Recent Development of Biodegradable Occlusion Devices for Intra-Atrial Shunts

Li,

Chen,

Xie

et al. 2024

Rev. Cardiovasc. Med.

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Advances in preclinical surgical therapy of cardiovascular diseases

Li,

Chang,

Song

2024

International Journal of Surgery

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Cardiovascular disease is the most common cause of death worldwide, resulting in millions of deaths annually. Currently, there are still some deficiencies in the treatment of cardiovascular diseases. Innovative surgical treatments are currently being developed and tested in response to this situation. Large animal models, which are similar to humans in terms of anatomy, physiology, and genetics, play a crucial role in connecting basic research and clinical applications. This article reviews recent preclinical studies and the latest clinical advancements in cardiovascular disease based on large animal models, with a focus on targeted delivery, neural regulation, cardiac remodeling, and hemodynamic regulation. It provides new perspectives and ideas for clinical translation and offers new methods for clinical treatment.

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A Novel Puncturable Atrial Septal Defect Occluder

Cited by 2 publications

References 29 publications

Recent Development of Biodegradable Occlusion Devices for Intra-Atrial Shunts

Recent Development of Biodegradable Occlusion Devices for Intra-Atrial Shunts

Advances in preclinical surgical therapy of cardiovascular diseases

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