A Novel Regimen for Perioral Dermatitis by Photodynamic Therapy

Abstract

Some patients with perioral dermatitis are not relieved despite many medications. These patients confront pain, psychological bother and social/occupational limitations. Being efficient for a wide variety of diseases including infectious inflammative degenerative or tumoral, photodynamic therapy holds a good chance to cure diseases of unknown origin, such as perioral dermatitis. This study presents the results of three women with chronic perioral dermatitis that persisted for years with partial response to medical regimen. They asked for photodynamic treatment to ease off their suffering. The duration of follow-up was up to five years. Following PDT (photodynamic therapy), the patients discontinued medications, redness decreased and eruption disappeared. In these patients, a single PDT treatment provided prolonged relief of perioral dermatitis for up to three years. These data are encouraging but not sufficient. Further study is warranted.

Manejo de la dermatitis perioral: reporte de un caso

“…El diagnóstico diferencial incluye rosácea, acné vulgar, dermatitis seborreica, dermatitis alérgica de contacto, queilitis irritante, sarcoidosis y angiofibromas 1,9,13 .…”

Coupled blue and red light-emitting diodes therapy efficacy in patients with rosacea: two case reports

“…In fact, PDT is routinely used by dermatologists in the treatment of moderate to severe acne vulgaris [50,51] and perioral dermatitis [18]. Rosacea shares several features with other dermatological diseases, especially acne.…”