A novel removal of Ni2+ ions from water solutions using dispersive solid-phase extraction method with nano Fe3O4/chitosan-acrylamide hydrogel

Arvand, Morteza Parsayi; Moghimi, Ali; Salehi, Narges

doi:10.21203/rs.3.rs-2439474/v1

Cited by 1 publication

(4 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…BCD is a crystalline compound and the XRD spectra provided here are broadly similar to those of other articles [12–32].…”

Section: Resultssupporting

confidence: 70%

“…where C 0 (mg.mL −1 ) and C e (mg.mL −1 ) are the initial and equilibrium concentrations of the analyte in aqueous solution, respectively. V (mL) is the volume of sample solution, and m (g) is the mass of nano-sorbent [31,32].…”

Section: Effectmentioning

confidence: 99%

“…The LOQ (Limit of Quantification) value has to be higher than the LOD, and it is defined as the lowest measured limit on the calibration curve, which was 2 mg.L −1 or 2000 µg.L −1 . Consequently, we conducted another round of the calibration curve experiment in a more precise setting, the lower limit was measured, and the calculated value for LOQ was 183 µg.L −1 [32].…”

Section: Pf =mentioning

confidence: 99%

“…The determination of Amitriptyline HCl has been done in a few studies using other methods such as air‐agitated liquid–liquid microextraction, Ionic liquid‐based single drop microextraction, dispersive liquid–liquid microextraction, and hollow fibre liquid‐phase microextraction but the use of the solid‐phase diffusion in this method reduces the consumption of toxic solvents, extraction time, and costs [6–29]. This method with its many applications in the separation and pre‐concentration of heavy metals and pharmaceutical molecules in the aqueous and biological samples has an important place in the preparation of samples [7–34]. In most studies using magnetic nanoparticles, it is necessary to cover these particles with a layer of materials such as polymers to increase their stability.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Preconcentration and measurement of trace Amitriptyline hydrochloride in water samples using magnetic nanoparticles with dispersive solid‐phase extraction

Amin,

Moghimi

2023

Micro & Nano Letters

Self Cite

View full text Add to dashboard Cite

In the separation and determination of trace amounts of drugs in aqueous samples, there is a major challenge in synthesizing highly efficient, cost‐effective, and easy‐to‐use adsorbents based on natural polymers, which are also biocompatible and biodegradable. In the proposed method, magnetite nanoparticles (Fe3O4) on chitosan (as the carrier) modified with β‐cyclodextrin (BCD) were used as a suitable adsorbent for the pre‐concentration and solid‐phase extraction of trace amounts of Amitriptyline HCl (hydrochloride). Ultraviolet spectrophotometer (λ = 236 nm) was the main instrument used for analyte detection and quantification. Moreover, X‐ray diffraction, Fourier transform infrared spectroscopy, Field Emission Scanning Electron Microscopy, and Energy‐Dispersive X‐ray were used for the identification and characterization of the structure and morphology of the adsorbent and to establish the formation of the synthesized magnetic nanosorbents, as well as to confirm the analyte binding to the adsorbent. Experimental variables affecting the extraction/pre‐concentration and determination of the analyte were investigated and optimized; pH of the sample solution, the amount of NaCl salt (in terms of ionic strength of the solution), the amount of adsorbent, temperature, adsorption time, and volume of the eluent (methanol) were the optimized parameters. Finally, the method was successfully applied for the determination of spiked Amitriptyline hydrochloride (HCl) in tap water and human urine samples. Also, High‐Performance Liquid Chromatography was performed on the aqueous samples to compare the proposed method with the USP (the United States Pharmacopeia) standard method of Amitriptyline HCl assay and after performing a t‐test (confidence level of 95%), no significant difference was observed between the two methods. High accuracy and precision (RSD = 3.91%), High analysis speed, few limitations, low expenses, pure extracted analyte, and low waste were the advantages of this method. This method was also compatible with many existing device methods. Under the optimized experimental conditions, the calibration graph was linear in the range of 0.183 to 50 mg.L−1 with a correlation coefficient of 0.996. RSD of the method was 3.91%, the limit of detection was 37.8 µg.L−1, the maximum sorption capacity of the adsorbent for Amitriptyline hydrochloride was 306.525 mg.g−1 and the preconcentration factor was 3.61. Eventually, the proposed method was compared to other methods that have been performed for the determination of Amitriptyline hydrochloride.

show abstract

“…BCD is a crystalline compound and the XRD spectra provided here are broadly similar to those of other articles [12–32].…”

Section: Resultssupporting

confidence: 70%

Section: Effectmentioning

confidence: 99%

Section: Pf =mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations