2023
DOI: 10.1111/cas.16015
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A novel iTreg‐related signature for prognostic prediction in lung adenocarcinoma

Jian Zhang,
Yan Li,
Yue Yang
et al.

Abstract: Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Most patients are diagnosed at an advanced stage, therefore it is crucial to identify novel prognostic biomarkers for LUAD. As important regulatory cells, inducible regulatory T cells (iTregs) play a vital role in immune suppression and are important for the maintenance of immune homeostasis. This study explored the prognostic value and therapeutic effects of iTreg‐related genes in LUAD. Data for LUAD patients, including immune infiltration … Show more

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Cited by 2 publications
(1 citation statement)
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“…The GO and KEGG pathway enrichment analyses highlighted the significant roles of ossification, cytokine pathways, and immune pathways in both diseases. SLA has been identified as a potential prognostic marker for pulmonary malignancies, particularly in adenocarcinomas [12]. However, the role of SLA in the pathogenesis of rheumatoid arthritis (RA) remains unclear and warrants further experimental research.…”
Section: Discussionmentioning
confidence: 99%
“…The GO and KEGG pathway enrichment analyses highlighted the significant roles of ossification, cytokine pathways, and immune pathways in both diseases. SLA has been identified as a potential prognostic marker for pulmonary malignancies, particularly in adenocarcinomas [12]. However, the role of SLA in the pathogenesis of rheumatoid arthritis (RA) remains unclear and warrants further experimental research.…”
Section: Discussionmentioning
confidence: 99%