A novel, sensitive method for determining benzo[a]pyrene-diones using high-performance liquid chromatography with post-column zinc reduction

Liao, Kai; Mayeno, Arthur N.; Reardon, Kenneth F.; Yang, Raymond S. H.

doi:10.1016/j.jchromb.2005.07.021

Cited by 4 publications

(1 citation statement)

References 21 publications

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“…These data indicate that PD •- or an oxygen-independent derivative of PD •- has a highly fluorescent state. This observation and interpretation are consistent with those made in related experiments on similar aromatic ketones such as benzo[a]pyrenediones . The radical anions of these latter compounds are known to form ketyl radicals by proton abstraction from residual water in the solvent, and these radicals have unique absorption and emission spectra .…”

Section: Resultssupporting

confidence: 90%

Spatial and Temporal Electrochemical Control of Singlet Oxygen Production and Decay in Photosensitized Experiments

et al. 2008

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Active spatial and temporal modulation of domains of singlet oxygen activity is demonstrated using electrochemical tools. Using singlet oxygen microscopy in photosensitized experiments, it is shown that singlet oxygen concentrations around an ultramicroelectrode can be controlled by applying a bias voltage to the electrode. Two phenomena that can be exploited separately or collectively are examined: (1) the singlet oxygen concentration can be altered by local oxidation or reduction of the photosensitizer, which is the precursor to singlet oxygen, and (2) the reduction of oxygen to produce the superoxide anion which, among other things, is an effective singlet oxygen quencher, results in a local decrease in the concentration of singlet oxygen around the electrode. Both of these phenomena depend significantly on the diffusion of molecules along concentration gradients established by the biased electrode. The results reported herein demonstrate that one can indeed exert local electrochemical control and readily manipulate the population of singlet oxygen produced in a photosensitized process.

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Section: Resultssupporting

confidence: 90%

Spatial and Temporal Electrochemical Control of Singlet Oxygen Production and Decay in Photosensitized Experiments

et al. 2008

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Determination of airborne particle-associated benz[a]anthracene-7,12-quinone using high-performance liquid chromatography with in-line reduction and fluorescence detection

Kameda

Goto

Toriba

et al. 2009

Journal of Chromatography A

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Cytochromes P450: A Structure-Based Summary of Biotransformations Using Representative Substrates

Brown

Reisfeld

Mayeno

2008

Drug Metabolism Reviews

125

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Cytochromes P450 (CYPs) are a superfamily of enzymes that metabolize the majority of xenobiotics in humans. This review presents a structure-based outline of CYP-catalyzed biotransformations of selected substrates, representing diverse structural classes of chemicals, ranging from drugs to toxicants. Data are presented in a tabular format for easy reference, with visual representations of all substrates and sites-of-attack. The major metabolites, isozymes responsible, chemical classification, and other information related to the biotransformation are provided. Pharmacophores proposed for the major CYP isozymes are discussed. This visual combination of substrates and biotransformation sites can serve as a useful reference for researchers.

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A novel, sensitive method for determining benzo[a]pyrene-diones using high-performance liquid chromatography with post-column zinc reduction

Cited by 4 publications

References 21 publications

Spatial and Temporal Electrochemical Control of Singlet Oxygen Production and Decay in Photosensitized Experiments

Spatial and Temporal Electrochemical Control of Singlet Oxygen Production and Decay in Photosensitized Experiments

Determination of airborne particle-associated benz[a]anthracene-7,12-quinone using high-performance liquid chromatography with in-line reduction and fluorescence detection

Cytochromes P450: A Structure-Based Summary of Biotransformations Using Representative Substrates

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