A novel series of O,O‐diethyl O‐(1,3‐disubstituted‐1,2,4‐triazol‐5‐yl) phosphorothioates. Part I. Synthesis and laboratory evaluation

Abstract

A novel series of O,O‐diethyl O‐(1‐R′‐3‐R″‐1,2,4‐triazol‐5‐yl) phosphorothioates, in in which R″ was an alkyl group and R″ was a radical characterised by the presence of a conjugated multiple bond, generally of a vinyl nature, has been synthesised and tested in the search for new insecticides. Several of the compounds showed a broad spectrum of activity, covering important species of Orthoptera, Hemiptera, Lepidoptera, Coleoptera, Diptera and mites. At the same time they were characterised by a relatively low oral toxicity to rats.