A novel synthesis of highly substituted imidazo[1,5-a]pyrazine derivatives by 3-CR/2-CR sequence

Challenge N- versus O-six-membered annulation: FeCl3-catalyzed synthesis of heterocyclic N,O-aminals

“…Given the established potencies of this class of N-ring-fused compounds, planned syntheses that simplify their preparation by using small building blocks and that lead, through appropriate transformations, to a product that becomes a substrate for another complexity-generating reaction, merit investigation [13][14][15].…”

Combined isocyanide-based multi-component Ullmann-type reaction: an efficient access to novel nitrogen-containing pentacyclic compounds

“…1). Thus, assembly of such a complex structures via effective and fast synthetic routes like multi-component reactions remains as a hot topic in organic chemistry [7][8][9][10][11][12][13].…”