A Novel Text Analysis Platform for Pharmacovigilance of Clinical Drugs

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“…The present study highlights the pharmacovigilance study of Siddha formulations used for the anti arthritic purpose 27 . The basic idea of conducting this pharmacovigilance survey is that more number of patients are turn to Siddha preparation because conventional allopathic drugs like non steroidal anti-inflammatory drugs (NSAIDs) or Disease Modifying anti-rheumatic drugs (DMARD's) are known for server side effects like urinary and water retention, gastric ulceration and some time chronic use may lead to chronic renal failure 28,29 . However the pharmacovigilance study on efficacy and side effect of the Siddha formulation has not been properly conducted in some Siddha formulation which are claimed to be 100 percent efficacious and devoid of adverse effects 30,31 .…”

Pharmacovigilance as Scientific Discovery: An Argument for Trans-Disciplinarity

“…For example, it has been proposed that medical journals adopt specific guidelines for the publications of adverse drug reaction case reports [12]. On another front, automated free-text analysis platforms are being developed in order to process patient narratives [13].…”

Signal Detection and their Assessment in Pharmacovigilance

“…There should be sufficient data to fully assess the relationship of the drug to the event. Various software and techniques are used for generation of good quality data [41,42]. Further, for establishing the relationship between cause and effect, various reports have been published but unfortunately there is no universally accepted method for assessing the causality of the ADRs.…”