A Novel Tool for the Assessment of Pain: Validation in Low Back Pain

Scholz, Joachim; Mannion, Richard; Hord, Daniela E.; Griffin, Robert S.; Rawal, Bhupendra; Zheng, Hui; Scoffings, Daniel; Phillips, Amanda; Guo, J.; Laing, Rodney; Abdi, Salahadin; Décosterd, Isabelle; Woolf, Clifford J.

doi:10.1371/journal.pmed.1000047

Cited by 234 publications

(203 citation statements)

References 55 publications

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“…21 The interview consisted of 16 questions exploring 46 items covering pain localization, evoked pains, and pain quality, along with further sensory qualities such as dysesthesia and numbness. The physical examination included 23 bedside tests that provided information about 39 items covering trophic and autonomic cutaneous signs, evoked pains, and sensory deficits using von Frey filaments, blunt pressure, brush, vibration, pinprick, temperature, passive movement, and the straight-leg-raising test.…”

Section: Interview and Bedside Examinationmentioning

confidence: 99%

Evaluation of Symptom Heterogeneity in Neuropathic Pain Using Assessments of Sensory Functions

Arning

Baron

2009

Neurotherapeutics

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Summary:Classification of neuropathic pain has been based on disease entities, anatomical localization, or histological observations. Over the past decade, there has been an explosion in our understanding of the basic mechanisms of neuropathic pain. The exciting advances in basic science are paralleled by the recognition from clinical investigations that neuropathic pain is not a monolithic entity, but instead presents as a composite of pain and other sensory symptoms. Attempts are under way to supplement the traditional classification with a classification that links pain and sensory symptoms with neurobiological mechanisms. This mechanism-or symptom-based classification takes both negative and positive sensory symptoms into account. By using a battery of several standardized quantitative sensory tests, the characteristic profile of sensory symptoms can be elucidated in each patient. Moreover, in questionnaires the verbal descriptors can depict the quality and intensity of the individual pain. The approach of classifying and subgrouping patients with neuropathic pain on the basis of symptoms or signs opens up new possibilities for stratifying patients in clinical trials. First, in clinical proof-of-concept trials the study population can be enriched prospectively on the basis of entry criteria defined a priori. This enrichment with patients who potentially require a specific treatment should increase the likelihood for positive trial outcomes. Second, in clinical practice it becomes possible to establish an individualized therapy-that is, to identify the particular patients who require a specific treatment option.

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Section: Interview and Bedside Examinationmentioning

confidence: 99%

Evaluation of Symptom Heterogeneity in Neuropathic Pain Using Assessments of Sensory Functions

Arning

Baron

2009

Neurotherapeutics

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“…Tools used to screen for the presence of neuropathic pain have been developed in English, French and German for use in European countries and the USA, and include the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) [2], the self-reported version of the LANSS (S-LANSS) [3], the Neuropathic Pain Questionnaire (NPQ) [4], the Douleur Neuropathique 4 questions (DN4) [5], painDETECT [6], ID-Pain [7] and the Standardized Evaluation of Pain (StEP) [8]. These tools rely on the patient’s verbal description of the nature of their pain and may include a simple clinical examination.…”

Section: Introductionmentioning

confidence: 99%

Translation and cultural adaptation of the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale into Arabic for use with patients with diabetes in Libya

Garoushi

Johnson

Tashani

2017

Libyan Journal of Medicine

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In Libya neuropathic pain is rarely assessed in patients with diabetes. The Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale is used worldwide to screen for neuropathic pain. There is no Arabic version of LANSS for use in Libya. The aim of this study was to develop an Arabic version of LANSS and to assess its validity and reliability in diabetic patients in Benghazi, Libya. LANSS was translated into Arabic by four bilingual translators and back translated to English by a university academic. Validity and reliability of the Arabic LANSS was assessed on 110 patients attending a Diabetes Centre in Benghazi. Concurrent validity was tested and compared with the Self-completed Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS). Test-retest reliability was conducted 1–2 weeks later. Internal consistency and inter-class correlation (ICC) between LANSS and S-LANSS was also tested. Internal consistency within first completion of the Arabic LANSS was acceptable (Cronbach’s alpha = 0.793) and similar to the Arabic S-LANSS (0.796) and the second completion of the Arabic LANSS (0.795). ICC between the Arabic LANSS and the Arabic S-LANSS was 0.999 (p < 0.001). Test-retest reliability (ICC) between first and second completions of the Arabic LANSS was 0.999 (p < 0.001). Kappa measurement of agreement between the two Arabic LANSS completions and S-LANSS was high on all seven items (Kappa >0.95, p < 0.0001). We concluded that the Arabic version of LANSS pain scale was valid and reliable for use on Libyan diabetic patients. This study provided results suggesting that the S-LANSS could also be used on diabetic patients.

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“…The most common chronic pain syndromes in humans are low back pain, arthritis of the joints, and headache 21 , whereas the most common chronic pain assays in current use for animal subjects involve experimental ligations of afferent fibers serving, and injection of inflammatory substances into, the hind paw 22 . Finally, whereas the most prevalent (and bothersome) clinical symptoms of chronic pain are deep, spontaneous (ongoing) pain and numbness 23,24 , and comorbidities like sleep disruption 21 , preclinical pain researchers continue to focus almost exclusively on measuring mechanical and thermal pain hypersensitivity (allodynia and hyperalgesia) 13,25 . Whether currently popular animal models are close enough to clinical reality or not is hard to say (is the glass half-empty, or is it half-full?…”

Section: Jeffrey S Mogilmentioning

confidence: 99%

Laboratory environmental factors and pain behavior: the relevance of unknown unknowns to reproducibility and translation

Mogil

2017

Lab Anim

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A Novel Tool for the Assessment of Pain: Validation in Low Back Pain

Abstract: Joachim Scholz and colleagues develop and validate an assessment tool that distinguishes between radicular and axial low back pain.

Cited by 234 publications

References 55 publications

Evaluation of Symptom Heterogeneity in Neuropathic Pain Using Assessments of Sensory Functions

Evaluation of Symptom Heterogeneity in Neuropathic Pain Using Assessments of Sensory Functions

Translation and cultural adaptation of the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale into Arabic for use with patients with diabetes in Libya

Laboratory environmental factors and pain behavior: the relevance of unknown unknowns to reproducibility and translation

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