A Novel Treatment Modality for Myofascial Pain Syndrome: Hyperbaric Oxygen Therapy

Kıralp, Mehmet Zeki; Uzun, Günalp; Dincer, Omit; Şen, Ahmet; Yıldız, Şenol; Tekin, Levent; Dursun, Hasan

doi:10.1016/s0027-9684(15)30815-4

Cited by 13 publications

(8 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…HBOT had rapid onset and a long lasting effect in patients with idiopathic trigeminal neuralgia [ 18 ]. It was found to be an effective treatment in cluster headaches and migraine [ 19 ] and fibromyalgia [ 20 , 21 ]. The potential benefits of HBOT in the treatment of CPRS were initially reported in a small double-blind, randomized, placebo-controlled study at a military hospital in Turkey on 71 patients with six-week history of traumatic CRPS of the upper extremity [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy

Katznelson

Segal

Clarke

2016

Pain Research and Management

View full text Add to dashboard Cite

Hyperbaric oxygen therapy (HBOT) is a treatment that delivers 100% oxygen at increased atmospheric pressures. The efficacy of HBOT for treating pain has been described in various animal pain models and may have clinical efficacy in the treatment of human chronic pain syndromes. We present our experience with posttraumatic Complex Regional Pain Syndrome (CRPS) type 2 in a patient who underwent 15 sessions of HBOT. A 41-year-old male with one-year history of CRPS of left foot followed by left ankle fracture demonstrated less pain, decreased swelling, less allodynia, and improvement in skin color and range of motion of the lower limb after 3 weeks of HBOT. Patient was back to work for the first time in over a year. HBOT may be considered as a valuable therapeutic tool in the treatment of long-standing CRPS.

show abstract

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy

Katznelson

Segal

Clarke

2016

Pain Research and Management

View full text Add to dashboard Cite

show abstract

“…The use of HBO 2 to treat chronic pain is the subject of ongoing research in both clinical and preclinical research. Clinically, HBO 2 treatment is reportedly effective in a variety of off-label applications, including some chronic pain conditions such as complex regional pain syndrome (formerly reflex sympathetic dystrophy syndrome) (Katznelson et al, 2016; Kiralp et al, 2004; Peach, 1995), fibromyalgia syndrome (Efrati et al, 2015; Yildiz et al, 2004), migraine or cluster headache (Di Sabato et al, 1993; Myers and Myers, 1995; Wilson et al, 1998), myofascial pain syndrome (Kiralp et al, 2009) and idiopathic trigeminal neuralgia (Gu et al, 2012). In the preclinical setting, HBO 2 has been shown to produce long-lasting pain relief in experimental animals (Chung et al, 2010; Gibbons et al, 2013; Warren et al, 1979).…”

Section: Introductionmentioning

confidence: 99%

Role of spinal GABA receptors in the acute antinociceptive response of mice to hyperbaric oxygen

et al. 2018

View full text Add to dashboard Cite

New pain treatments are in demand due to the pervasive nature of pain conditions. Hyperbaric oxygen (HBO) has shown potential in treating pain in both clinical and preclinical settings, although the mechanism of this effect is still unknown. The aim of this study was to investigate whether the major inhibitory neurotransmitter γ-aminobutyric acid (GABA) is involved in HBO-induced antinociception in the central nervous system (CNS). To accomplish this goal, pharmacological interactions between GABA drugs and HBO were investigated using the behavioral acetic acid abdominal constriction test. Western blotting was used to quantify protein changes that might occur as a result of the interactions. GABA but not GABA receptor antagonists dose-dependently reduced HBO antinociception, while antagonism of the GABA reuptake transporter enhanced this effect. Western blot results showed an interaction between the pain stimulus and HBO on expression of the phosphorylated β3 subunit of the GABA receptor at S408/409 in homogenates of the lumbar but not thoracic spinal cord. A significant interaction was also found in neuronal nitric oxide synthase (nNOS) expression in the lumbar but not thoracic spinal cord. These findings support the notion that GABA may be involved in HBO-induced antinociception at the GABA receptor but indicate that more study will be needed to understand the intricacies of this interaction.

show abstract

“…MPS is usually managed by stretch and massage, thermotherapy, electrotherapy, laser therapy, dry needling, acupuncture, shockwave therapy, botulinum toxin type A injection, trigger point injections, pharmacological methods, and according to a recent report even hyperbaric oxygen therapy can be used. [1617181920] Pharmacological treatment methods include diclofenac patch, tramadol, tropisetron, opioids, lidocaine patch, tizanidine, benzodiazepines, cyclobenzaprine, thiocolchicoside, gabapentin, pregabalin, amitriptyline, duloxetine, sumatriptan, botulinum type A toxin, ketamine, L-tryptophan, and memantine. [21] Although medications provide improvement in acute cases, they carry a risk of adverse effects and offer only symptomatic relief.…”

Section: Myofascial Pain Syndrome and Current Palliative Methodsmentioning

confidence: 99%

The possible role of meditation in myofascial pain syndrome: A new hypothesis

Panta

2017

Indian J Palliat Care

View full text Add to dashboard Cite

Background of Hypothesis:Myofascial pain syndrome (MPS) is the most common musculoskeletal pain disorder of the head and neck area. In the past, several theories were put forth to explain its origin and nature, but none proved complete. Myofascial pain responds to changing psychological states and stress, anxiety, lack of sleep, anger, depression and chronic pain are direct contributional factors. Myofascial pain syndrome may be considered as a psychosomatic disorder. There are numerous accepted palliative approaches, but of all, relaxation techniques stand out and initiate healing at the base level. In this article, the connection between mental factors, MPS and meditation are highlighted. Recent literature has shed light on the fundamental role of free radicals in the emergence of myofascial pain. The accumulating free radicals disrupt mitochondrial integrity and function, leading to sustenance and progression of MPS. Meditation on the other hand was shown to reduce free radical load and can result in clinical improvement. ‘Mindfulness’ is the working principle behind the effect of all meditations, and I emphasize that it can serve as a potential tool to reverse the neuro-architectural, neurobiological and cellular changes that occur in MPS.Conclusions:The findings described in this paper were drawn from studies on myofascial pain, fibromyalgia, similar chronic pain models and most importantly from self experience (experimentation). Till date, no hypothesis is available connecting MPS and meditation. Mechanisms linking MPS and meditation were identified, and this paper can ignite novel research in this direction.

show abstract

A Novel Treatment Modality for Myofascial Pain Syndrome: Hyperbaric Oxygen Therapy

Cited by 13 publications

References 7 publications

Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy

Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy

Role of spinal GABA receptors in the acute antinociceptive response of mice to hyperbaric oxygen

The possible role of meditation in myofascial pain syndrome: A new hypothesis

Contact Info

Product

Resources

About