A novel triple-network hydrogel based on borate ester groups: from structural modulation to rapid wound hemostasis

Abstract

Supramolecular hydrogels have received extensive attention due to their soft texture, strong hygroscopicity, and good biocompatibility. These materials become particularly attractive to sensing, tissue engineering, fluorescent encoding, wound healing, etc....

Hydrogels with Reversible Crosslinks for Improved Localised Stem Cell Retention: A Review

“…A novel triple‐network supramolecular hydrogel based on boric acid/polyvinyl alcohol/guanosine was constructed via non‐covalent crosslinking. They confirmed biocompatibility, shape adaption and optical information storage capacity; also, the rapid hemostatic ability and the capacity of the hydrogel to promote wound healing were established both in vitro and in vivo [255] …”

“…They confirmed biocompatibility, shape adaption and optical information storage capacity; also, the rapid hemostatic ability and the capacity of the hydrogel to promote wound healing were established both in vitro and in vivo. [255] Another late research comes from Shao et al, who developed a self-adaptive multifunctional hydrogel that is injectable and has self-healing This hydrogel was made via a boronic ester-based reaction between the phenylboronic acid groups of the 3-carboxyl-4-fluorophenylboronic acid-grafted quaternised chitosan and the hydroxy groups of the polyvinyl alcohol. Additionally, the system was loaded with the proangiogenic drug of desferrioxamine.…”

Antibacterial, ROS scavenging and angiogenesis promoting ϵ-Polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing

“…There were no significant differences between 15% GPL and 15% GPL/CTLP-MPs hydrogels, their swelling trends were similar (figure 2(C)). The borate ester bond can rapidly break down under acidic conditions, which accelerates the degradation of hydrogels [24][25][26]. To investigate how the hydrogels degrade, they were exposed to both acidic (pH = 5.5) and neutral (pH = 7.4) environments.…”

Structure–activity relationship of drug conjugated polymeric materials against uropathogenic bacteria colonization under in vitro and in vivo settings

“…[24][25][26] One way to find a solution to these problems is exploring different polymers and utilizing their antibacterial potentials. [27][28][29][30][31] The polymers which were studied extensively for evaluating their antimicrobial properties include polyurethane, pyridinium polymers, alkoxysilanes, polyionenes and polyethyleneimine. [32][33][34][35] These compounds' low propensity to develop resistance and their quick bactericidal impact are just two of their many benefits.…”