A novel zinc phthalocyanine-indometacin photosensitizer with “Three-in-one” cyclooxygenase-2-driven dual targeting and aggregation inhibition for high-efficient anticancer therapy

Targeted Drug Delivery System Based on Copper Sulfide for Synergistic Near-Infrared Photothermal Therapy/Photodynamic Therapy/Chemotherapy of Triple Negative Breast Cancer

“…Compound 1 was prepared by the literature method . A mixture of 3-nitrophthalonitrile (1.73 g, 10 mmol) and butylparaben (1.94 g, 10 mmol) was stirred and dissolved in dry dimethyl sulfoxide (DMSO) (25 mL) completely.…”

“…Compound 2 was prepared by the literature method . A mixture of compound 1 (0.32 g, 1 mmol) and 1,2-dicyanobenzene (0.64 g, 9 mmol) was stirred in dry n -pentanol (10 mL) at 110 °C under N 2 until the solids were completely dissolved.…”

Synthesis, characterization, and α‐glucosidase, cholinesterases, and tyrosinase inhibitory effects of axial substituted silicon and peripheral tetra‐substituted copper (II), manganese (III) phthalocyanines

“…In last years, there have been many studies on the biological studies of phthalocyanine. It has been determined that phthalocyanine compounds substituted with various ligands have antimicrobial, [5] anticancer, [6] antioxidant, [7] anti-glucosidase, [8] anti-tyrosinase, [9] anticarbonic anhydrase, [10] antiurease, [11] anticholinesterase, [12] antixanthine oxidase, [13] electrochemical, [14][15][16] and photodynamic therapy properties. [17] α-Glucosidase, hydrolyze polysaccharides or oligosaccharides to generate glucose units, has a key role in carbohydrate metabolism.…”

Synthesis of Axial Bis(benzo[d][1,3]dioxol‐5‐ylmethoxy)phthalocyaninato Silicon (IV): Photophysical and Photochemical Properties and Docking Studies on DNA‐SiPc Interactions

“…These compounds carry the necessary conditions with their features such as non-aggregation. [15][16] Phthalocyanine compounds with these properties have the potential to be used as photosensitizers. Therefore, although it is promising for photodynamic therapy, it is expected to contribute to the development of a new treatment method.…”

“…For this reason, in this study, the synthesis of axial phthalocyanines known for their fluorescent properties was aimed. These compounds carry the necessary conditions with their features such as non‐aggregation [15–16] . Phthalocyanine compounds with these properties have the potential to be used as photosensitizers.…”