A numerical investigation of the mechanics of intracranial aneurysms walls: Assessing the influence of tissue hyperelastic laws and heterogeneous properties on the stress and stretch fields

In vivo mechanical characterization of arterial wall using an inverse analysis procedure: application on an animal model of intracranial aneurysm

“…With respect to the bibliography and for an isotropic incompressible Fung-like material law applied to the artery wall with material constants a and b : for UIA, a = 353.6 kPa and b = 16.7 were reported [46,47]; a = 176.8 kPa and b = 16.7 were identified experimentally as parameters associated with ruptured aneurysms [18,41,47]. The material constants detailed in table 2 were congruent with these data for S1 and S2, which validated the proposed in vivo parameter identification procedure.…”

“…The FSI between the flows and the aneurysm wall was computed in C1 and C2 with the two-element ( a , b ) hyperelastic model. A parametric study was performed for each study subject with 51 ( a , b ) couples considered for C1, C2 and in each case D1, D2 and D3: based on the literature data, a ranged between 85 and 645 kPa, b ranged between 14.4 and 17.6 [18,41,46,47]. Assuming that the luminal volume variation true0 normalΔ V n u m depends only on the model parameters, a volumetric function can be defined as:…”

“…To quantify the aneurysm stress state for the model parameters identified, the first principal Cauchy stress field of the aneurysm inner wall true0 σ 1 was considered [47]. The true0 < σ 1 > mean of the aneurysm area was computed for the C2 and compared to the C1.…”

OpenFOAM-preCICE: Coupling OpenFOAM with External Solvers for Multi-Physics Simulations

“…The most prominent example for CHT is chtMultiRegionFoam [14] and the training code conjugateHeatFoam [15]. For FSI, prominent examples are the foam-extend packages fsiFoam [16] (studied e.g., by Luofeng et al [17]) and solids4foam [18] (used, e.g., by Oliveira et al [19]), as well as the training code simpleFsi [20]. The same approach is also followed by Wagner et al [21] to extend OpenFOAM to FSI of 2D membranes.…”

“…For all simulations presented in this section, we have used OpenFOAM v2112, preCICE v2.4.0, and the OpenFOAM adapter v1.1.0. A virtual machine image is available 18 for reproducibility, based on the preCICE Demo Virtual Machine 19 . Note that this section aims to validate only the adapter.…”