In the core accretion scenario for the formation of planetary rocky cores, the first step toward planet formation is the growth of dust grains into larger and larger aggregates and eventually planetesimals. Although dust grains are thought to grow from the submicron sizes typical of interstellar dust to micron size particles in the dense regions of molecular clouds and cores, the growth from micron size particles to pebbles and kilometre size bodies must occur in the high densities reached in the mid-plane of protoplanetary disks. This critical step in the formation of planetary systems is the last stage of solids evolution that can be observed directly in young extrasolar systems before the appearance of large planetary-size bodies.Tracing the properties of dust in the disk mid-plane, where the bulk of the material for planet formation resides, requires sensitive observations at long wavelengths (sub-mm through cm waves). At these wavelengths, the observed emission can be related to the dust opacity, which in turns depend on to the grain size distribution. In recent years the upgrade of the existing (sub-)mm arrays, the start of ALMA Early Science operations and the upgrade of the VLA have significantly improved the observational constraints on models of dust evolution in protoplanetary disks. Laboratory experiments and numerical simulations led to a substantial improvement in the understanding of the physical processes of grain-grain collisions, which are the foundation for the models of dust evolution in disks.In this chapter we review the constraints on the physics of grain-grain collisions as they have emerged from laboratory experiments and numerical computations. We then review the current theoretical understanding of the global processes governing the evolution of solids in protoplanetary disks, including dust settling, growth, and radial transport. The predicted observational signatures of these processes are summarized.We discuss the recent developments in the study of grain growth in molecular cloud cores and in collapsing envelopes of protostars as these likely provide the initial conditions for the dust in protoplanetary disks. We then discuss the current observational evidence for the growth of grains in young protoplanetary disks from millimeter surveys, as well as the very recent evidence of radial variations of the dust properties in disks. We also include a brief discussion of the constraints on the small end of the grain size distribution and on dust settling as derived from optical, near-, and mid-IR observations. The observations are discussed in the context of global dust evolution models, in particular we focus on the emerging evidence for a very efficient early growth of grains in disks and the radial distribution of maximum grain sizes as the result of growth barriers in disks. We will also highlight the limits of the current models of dust evolution in disks including the need to slow the radial drift of grains to overcome the migration/fragmentation barrier.