A numerical study on the thermal response in multi-layer of skin tissue subjected to heating and cooling procedures

Chaudhary, Rajneesh Kumar; Chaurasiya, Vikas; Awad, Mohamed M.; Singh, Jitendra

doi:10.1140/epjp/s13360-021-02322-x

Cited by 23 publications

(3 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Undoubtedly, the analysis of its temperature distribution is key to understanding the mechanism of RF heating. For the problem, Chaudhary et al have focused on the research of numerical calculations, [21][22][23][24] and Shrivastava et al have concentrated on the study of animal experiments. [25][26][27] The integration of numerical calculations with experimental results allows for mutual validation, thereby helping to improve the reliability of predicting temperature distributions.…”

Section: Introductionmentioning

confidence: 99%

Selective and Controllable Mechanism of the Temperature Field in Pig Skin under Radiofrequency Heating

Zhu,

Xie,

Shu

et al. 2024

Preprint

View full text Add to dashboard Cite

Radiofrequency heating is widely used in medical aesthetics, which essentially achieves the contraction of collagen fibers in the dermis by increasing its temperature. The paper aimed to study the selective and controllable mechanism for the temperature field in 0.02 kg ex-vivo pig skin samples obtained from the 25 kg Bama pig under radiofrequency heating by the finite element method and relevant experiments. A heating model of pig skin was constructed at 4 MHz with a mixed heating mode of fixed-point and reciprocating sliding. Based on the mixed heating, the dermis was heated preferentially and uniformly due to its high electrical conductivity and thermal conductivity compared to other tissue layers. It allowed the dermis temperature 55.1 ℃ to remain at a dynamic plateau period with an error of 0.1 ℃, and the mean specific absorption rate across the entire pig was under 2 W/kg within 30 s in this period. The verification experiment on the pig skin samples under the same conditions showed consistent temperature distributions between the model and experiment, and the dermis collagen fibers structure was clear without tissue damage. The research results provide useful guidance for radiofrequency application practitioners to selectively control skin temperature distributions.

show abstract

Section: Introductionmentioning

confidence: 99%

Selective and Controllable Mechanism of the Temperature Field in Pig Skin under Radiofrequency Heating

Zhu,

Xie,

Shu

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…The diversity of mechanisms involved in tumor invasion requires different areas of knowledge to contribute to the development of treatment strategies [16,17]. Mathematical modeling can provide both qualitative and quantitative information to better understand the complex behavior of biological tissues, particularly tumors [18][19][20]. That information helps in interpreting the complicated interactions between tumors and their microenvironment.…”

Section: Introductionmentioning

confidence: 99%

Mathematical Modeling of Spherical Shell-Type Pattern of Tumor Invasion

2023

View full text Add to dashboard Cite

Cancer cell migration, as the principal element of tumor invasion, involves different cellular mechanisms. Various modes of cell migration including single and collective motions contribute to the invasion patterns. The competition between adhesive cell–cell and cell–matrix forces is a key factor that determines such patterns. In this paper, we study a distinct shell-type mode of tumor invasion observed in brain and breast tumors. In this mode, cells at the outer layer of the tumor collectively move away from the core and form a shell-type shape. Both the core and the shell sustain a sharp interface between cells and the surrounding matrix. To model the preserved interface, we adopted a Cahn–Hilliard-type free energy relation with the contribution of the interfacial stress. This nonconvex form of free energy allows for cells to remain together and preserve the tumor core via adhesive cell–cell forces while separating the core from the surrounding matrix across a continuous sharp interface. In addition, the motion of the shell was modeled using the chemotactic migration of cells in response to the gradient of nutrients. The associated fluxes of cells were implemented in a general form of balance law. A non-Michaelis–Menten kinetics model was adopted for the proliferation rate of cells. The flux of nutrients was also modeled using a simple diffusion equation. The comparison between the model predictions and experimental observations indicates the ability of the model to manifest the salient features of the invasion pattern.

show abstract

“…Due to the diversity and complexity of animal skin tissue, it is necessary to use finite element method and cooperate with experiments to understand this mechanism. [10][11][12][13] Here, a three-dimensional (3D) heating model of pig skin tissue was established using the finite element method based on a fixed and reciprocating sliding heating mode at a frequency of 4MHz. The heating rate and temperature distribution of the epidermis, dermis, and subcutaneous tissue (SCT) in pig skin had been investigated.…”

mentioning

confidence: 99%

Selective and Controllable Heating Model of Pig Skin under Radiofrequency Heating and Relevant Experimental Verification

Zhu,

Xie,

Shu

et al. 2023

Preprint

View full text Add to dashboard Cite

Radiofrequency heating is widely used in the field of medical aesthetics, which essentially achieves the contraction of collagen in the dermis tissue by increasing its temperature. The paper aimed to study the selective and controllable heating mechanism of pig skin under radiofrequency heating by the finite element method and relevant experiments. A heating model of pig skin was constructed at 4 MHz radiofrequency with a mixed heating mode of fixed-point and reciprocating sliding. Based on the mixed radiofrequency heating, the dermis layer in pig skin was heated rapidly and uniformly due to its relatively high electrical conductivity and thermal conductivity compared to other skin tissue layers. This allowed the dermis temperature \(\stackrel{\text{-}}{\text{Σ}}\text{=55.1±0.1°C}\) to remain at a dynamic plateau period. Under the same conditions, the fresh hairless skin of young pig was heated to verify the model, and the experimental and theoretical results are consistent. The research results have a certain guiding significance in forecasting the changes in human skin temperature field under radiofrequency heating and provide novel insights for future research in related fields.

show abstract

A numerical study on the thermal response in multi-layer of skin tissue subjected to heating and cooling procedures

Cited by 23 publications

References 54 publications

Selective and Controllable Mechanism of the Temperature Field in Pig Skin under Radiofrequency Heating

Selective and Controllable Mechanism of the Temperature Field in Pig Skin under Radiofrequency Heating

Mathematical Modeling of Spherical Shell-Type Pattern of Tumor Invasion

Selective and Controllable Heating Model of Pig Skin under Radiofrequency Heating and Relevant Experimental Verification

Contact Info

Product

Resources

About