A one‐year survey on the use of a powder from Rosa canina lito in acute exacerbations of chronic pain

Abstract

This pilot surveillance included 152 patients with acute exacerbations of chronic pain, 124 (Back group) with non-specific low back pain (NSLBP), 20 with NSLBP overridden by osteoarthritic pain (Knee-Hip group), and eight with specific LBP (included in the safety analysis). Patients were recommended the rose hip and seed powder Litozin at a dose providing up to 3 mg of galactolipid/day for up to 54 weeks. Clinical symptoms and well-being were assessed every 6 weeks. The patients also kept a diary of their pain and the requirement for rescue medication. Data were analysed by intention to treat with last observation carried forward. Only 77 patients completed the year of surveillance. Multivariate analysis suggested an appreciable overall improvement during the surveillance, irrespective of group, and this was reflected for most of the individual measures in repeated measures ANOVA. The degree and time-course of improvement echoed that seen in similar surveillances of patients receiving an aqueous extract of Harpagophytum. Multiple regression analyses indicated that percentage changes from baseline tended to be greater in patients with greater degrees of pain and disability, but were otherwise largely unrelated to the patients' characteristics. There were no serious adverse events. The rose hip and seed powder, Litozin, seems to deserve further, more definitive studies as a possible option in long-term management of NSLBP with or without osteoarthritic pain.

The role of rose hip (Rosa canina L) powder in alleviating arthritis pain and inflammation – part II animal and human studies

“…Reductions in pain were again accessed using questionnaires, and the study design was the same as used in the earlier study. 30 Interestingly, reductions in pain and disability scores in this study with the …”

“…The present study can therefore not document that rose hip works in lower back pain but the study stimulates to further research on the present group of patients. 30 In addition, the significant decrease in pain, which was first recorded after 3 months of treatment, continued to manifest during the subsequent 9 months of treatment, indicating that pain reduction, whatever the magnitude, continues with long-term rose hip treatment. This is important information, especially as the same observation was made in a study on pain reduction in rheumatoid patients treated with the same rose hip powder for 6 months.…”

“…A total of 152 patients, among whom 124 suffered from severe back pain, eleven had pains related to the hip, nine had pains related to the knees, and eight participants with specific lower back pain, took part in the pilot clinical study. 30 The main objective of the study was to find out if a R. canina preparation (again based on the subspecies Lito) containing an equal amount of seeds and shells would reduce acute exacerbations of chronic back pain. The study was on the intention-to-treat basis.…”

Medicinal herbs as possible sources of anti-inflammatory products

“…Changes were more pronounced in case of patients with higher degrees of pain and disability, but were generally unrelated to patient characteristics. No adverse effects were noted [45]. Another evidence of the anti-inflammatory action of galactolipid was demonstrated in a paper in which three randomized controlled trials involving 287 arthritic patients with a median treatment period of 3 months were performed.…”

5 Medicinal Plants Used in Iranian Traditional Medicine for Low Back Pain: A Quick Review

“…The main active ingredient of this herb is colchicine, a kind of alkaloid, was found to be effective in control of the pain and inflammation [40,41].…”