A pandemic center’s experience of managing pregnant women with COVID‐19 infection in Turkey: A prospective cohort study

Abstract

Objective To evaluate the course and effect of coronavirus disease 2019 (COVID‐19) on pregnant women followed up in a Turkish institution. Methods A prospective, single tertiary pandemic center cohort study was conducted on pregnant women with confirmed or suspected severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. Positive diagnosis was made on a real‐time polymerase chain reaction (RT‐PCR) assay of a nasopharyngeal and oropharyngeal specimen. Demographic features, clinical characteristics, and maternal and perinatal outcomes were evaluated. Results SARS‐CoV‐2 was suspected in 100 pregnant women. Of them, 29 had the diagnosis confirmed by RT‐PCR. Eight of the remaining 71 cases had clinical findings highly suspicious for COVID‐19. Ten (34.5%) of the confirmed cases had co‐morbidities. Cough (58.6%) and myalgia (51.7%) were the leading symptoms. COVID‐19 therapy was given to 10 (34.5%) patients. There were no admissions to the intensive care unit. Pregnancy complications were present in 7 (24.1%) patients. Half of the births (5/10) were cesarean deliveries. None of the neonates were positive for SARS‐CoV‐2. Samples of breastmilk were also negative for the virus. Three neonates were admitted to the neonatal intensive care unit. Conclusion The clinical course of COVID 19 during pregnancy appears to be mild in the present study.

Updated experience of a tertiary pandemic center on 533 pregnant women with COVID‐19 infection: A prospective cohort study from Turkey

“…The present study is an updated version of the previously published research by Sahin et al [4]. A precise diagnosis of COVID-19 infection was made by the detection of SARS-CoV-2 positivity on RT-PCR analysis of nasopharyngeal and oropharyngeal specimens collected from the participants [4]. The following information was prospectively recorded by the researchers: maternal age; gravidity; parity; number of living children; previous miscarriages; pre-pregnancy body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters; BMI ≥30 was defined as obese); route of…”

“…The present study is an updated version of the previously published research by Sahin et al [4]. A precise diagnosis of COVID-19 infection was made by the detection of SARS-CoV-2 positivity on RT-PCR analysis of nasopharyngeal and oropharyngeal specimens collected from the participants [4].…”

“…Ankara City Hospital is one of the leading pandemic centers in Turkey and the authors previously shared their experience on pregnant women with COVID-19 infection [4]. As the number of cases has increased dramatically since the initial publication of that study, the authors intend to share their updated experience on pregnant women with COVID-19.…”

“…The number of ICUs and mechanical ventilation devices remained sufficient for the number of serious cases during the pandemic period. The whole organization was conducted together with national a scientific committee consisting of experts in their fields [4,5,25].…”

SARS-CoV-2 Infection in Pregnancy: A Case Report on the First Emergency Cesarean Section in Vietnam and Literature Review

“…There is ample evidence that viral infections can cause serious complications during pregnancy. However, there still have been conflicting results on the effects of COVID-19 in pregnancy [8].…”