A Panton-Valentine Leucocidin (PVL)-Positive Community-Acquired Methicillin-Resistant
            <i>Staphylococcus aureus</i>
            (MRSA) Strain, Another Such Strain Carrying a Multiple-Drug Resistance Plasmid, and Other More-Typical PVL-Negative MRSA Strains Found in Japan

Takizawa, Yui; Taneike, Ikue; Nakagawa, Saori; Oishi, Tomohiro; Nitahara, Yoshiyuki; Iwakura, Nobuhiro; Ozaki, Kyoko; Takano, Misao; Nakayama, Teruko; Yamamoto, Tatsuo

doi:10.1128/jcm.43.7.3356-3363.2005

Cited by 134 publications

(163 citation statements)

References 44 publications

Supporting

Mentioning

153

Contrasting

Unclassified

Order By: Relevance

“…The results suggest that the C-MRSA strains isolated from patients with impetigo and SSSS have evolved not only ␤-lactam resistance but also multidrug resistance. Recently, skin and soft tissue infections and severe necrotizing pneumonia caused by C-MRSA strains carrying the Panton-Valentine leukocidin gene (pvl) have become a serious problem (6,21,44,51). Although screening for pvl was carried out by PCR, no pvl was detected among the C-MRSA strains used in this study (data not shown).…”

Section: Discussionmentioning

confidence: 79%

Antimicrobial Agent of Susceptibilities and Antiseptic Resistance Gene Distribution among Methicillin-Resistant Staphylococcus aureus Isolates from Patients with Impetigo and Staphylococcal Scalded Skin Syndrome

et al. 2006

View full text Add to dashboard Cite

The susceptibilities to antimicrobial agents of and distributions of antiseptic resistance genes in methicillinresistant Staphylococcus aureus (MRSA) strains isolated between 1999 and 2004 in Japan were examined. The data of MRSA strains that are causative agents of impetigo and staphylococcal scalded skin syndrome (SSSS) were compared with those of MRSA strains isolated from patients with other diseases. The susceptibilities to antiseptic agents in MRSA isolates from patients with impetigo and SSSS were higher than those in MRSA isolates from patients with other diseases. The distribution of the qacA/B genes in MRSA strains isolated from patients with impetigo and SSSS (1.3%, 1/76) was remarkably lower than that in MRSA strains isolated from patients with other diseases (45.9%, 95/207). Epidemiologic typings of staphylococcal cassette chromosome mec (SCCmec) and pulsed-field gel electrophoresis (PFGE) showed that MRSA strains isolated from patients with impetigo and SSSS had type IV SCCmec (75/76), except for one strain, and 64.5% (49/76) of the strains had different PFGE types. In addition, the patterns of restriction digestion of all tested qacA/B plasmid in MRSA isolates having different PFGE types were identical. The results showed that a specific MRSA clone carrying qacA/B was not prevalent, but qacA/B was spread among health care-associated MRSA strains. Therefore, it was concluded that the lower distribution rate of qacA/B resulted in higher susceptibilities to cationic antiseptic agents in MRSA isolated from patients with impetigo and SSSS.

show abstract

Section: Discussionmentioning

confidence: 79%

Antimicrobial Agent of Susceptibilities and Antiseptic Resistance Gene Distribution among Methicillin-Resistant Staphylococcus aureus Isolates from Patients with Impetigo and Staphylococcal Scalded Skin Syndrome

et al. 2006

View full text Add to dashboard Cite

show abstract

“…PVL-negative CA-MRSA included ST8 strain NN50 (18), ST88 strain NN51 (39), ST89 strain NN7 (39), and ST91 strain NN15 (39); ST88, ST89, and ST91 strains were from bullous impetigo and were exfoliative toxin (ET)-positive. The New York/Japan ST5/SCCmecII clone (a major HA-MRSA clone in Japan), used in this study, included reference strains Mu50 and N315 and clinical strains I6 and I8 (34). PVL-positive ST8 CA-MRSA USA300 included the type strain (USA300-0114) and strains NN36 and NN47 isolated in Japan (13).…”

Section: Distribution Of Pvl-positive St30 Mrsa In Japanmentioning

confidence: 99%

“…CA-MRSA (34,37,38). In this study, we investigated PVL-positive ST30 MRSA since the 1980s in Japan focusing on its evolution and virulence.…”

mentioning

confidence: 99%

Evolution and virulence of Panton-Valentine leukocidin-positive ST30 methicillin-resistant Staphylococcus aureus in the past 30 years in Japan

et al. 2012

Self Cite

View full text Add to dashboard Cite

“…Moreover, two lukS/F-PVpositive MRSA strains were isolated in 2003 and 2004 from Japanese hospitals (Takizawa et al 2005), emphasizing the necessity to monitor lukS/F-PV-positive MRSA clones for preventing the spread of infection. SCCmec typing is useful for characterizing CA-MRSA clones.…”

mentioning

confidence: 99%

Genetic Diagnosis of Community-Acquired MRSA: A Multiplex Real-Time PCR Method for Staphylococcal Cassette Chromosome mec Typing and Detecting Toxin Genes

Motoshima

Yanagihara

Morinaga

et al. 2010

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

A Panton-Valentine Leucocidin (PVL)-Positive Community-Acquired Methicillin-Resistant Staphylococcus aureus (MRSA) Strain, Another Such Strain Carrying a Multiple-Drug Resistance Plasmid, and Other More-Typical PVL-Negative MRSA Strains Found in Japan

Abstract: Community-acquired methicillin-resistant

Cited by 134 publications

References 44 publications

Antimicrobial Agent of Susceptibilities and Antiseptic Resistance Gene Distribution among Methicillin-Resistant Staphylococcus aureus Isolates from Patients with Impetigo and Staphylococcal Scalded Skin Syndrome

Antimicrobial Agent of Susceptibilities and Antiseptic Resistance Gene Distribution among Methicillin-Resistant Staphylococcus aureus Isolates from Patients with Impetigo and Staphylococcal Scalded Skin Syndrome

Evolution and virulence of Panton-Valentine leukocidin-positive ST30 methicillin-resistant Staphylococcus aureus in the past 30 years in Japan

Genetic Diagnosis of Community-Acquired MRSA: A Multiplex Real-Time PCR Method for Staphylococcal Cassette Chromosome mec Typing and Detecting Toxin Genes

Contact Info

Product

Resources

About