A paper-based oxygen generating platform with spatially defined catalytic regions

Ochoa, Manuel; Rahimi, Rahim; Huang, Tiffany L.; Alemdar, Neslihan; Khademhosseini, Ali; Dokmeci, Mehmet R.; Ziaie, Babak

doi:10.1016/j.snb.2014.02.021

Cited by 23 publications

(20 citation statements)

References 26 publications

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“…Wounds are common forms of injury in tissues with most acute wounds healing properly without medical interventions. However, some of the chronic wounds will have delayed healing or lead to unhealed open wounds or ulceration 78,79 . The blood supply is an essential component in wound healing that aids in the formation of connective tissue.…”

Section: Wound Healingmentioning

confidence: 99%

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Breathing life into engineered tissues using oxygen-releasing biomaterials

et al. 2019

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Engineering three-dimensional (3D) tissues in clinically relevant sizes have demonstrated to be an effective solution to bridge the gap between organ demand and the dearth of compatible organ donors. A major challenge to the clinical translation of tissue-engineered constructs is the lack of vasculature to support an adequate supply of oxygen and nutrients post-implantation. Previous efforts to improve the vascularization of engineered tissues have not been commensurate to meeting the oxygen demands of implanted constructs during the process of homogeneous integration with the host. Maintaining cell viability and metabolic activity during this period is imperative to the survival and functionality of the engineered tissues. As a corollary, there has been a shift in the scientific impetus beyond improving vascularization. Strategies to engineer biomaterials that encapsulate cells and provide the sustained release of oxygen over time are now being explored. This review summarizes different types of oxygen-releasing biomaterials, strategies for their fabrication, and approaches to meet the oxygen requirements in various tissue engineering applications, including cardiac, skin, bone, cartilage, pancreas, and muscle regeneration.

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Section: Wound Healingmentioning

confidence: 99%

“…In another study, a cost-effective and portable device was developed to release oxygen to a targeted damaged tissue area without affecting other undamaged tissues 78 . The oxygen delivery device consisted of parchment paper and PDMS, on which microfluidic channels were fabricated.…”

Section: Wound Healingmentioning

confidence: 99%

Breathing life into engineered tissues using oxygen-releasing biomaterials

et al. 2019

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“…Mechanisms involving intermediate reaction products and kinetics using popular catalysts such as manganese oxide were previously explored [ 37 ]. An efficient parchment paper material for local wound oxygenation was demonstrated [ 38 ]. In part, the research direction is also driven towards the investigation of single compartment hydrogen peroxide clean fuel cells, such as with poly(3,4-ethylenedioxythiophene) cathodes [ 39 ], integration of micromotors to power gaseous hydrogen/oxygen fuel cells [ 40 ] and related chemo-mechano-electrical energy converters [ 41 ].…”

Section: Introductionmentioning

confidence: 99%

Parameters Optimization of Catalytic Tubular Nanomembrane-Based Oxygen Microbubble Generator

Naeem

Zhang

et al. 2020

Micromachines

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A controllable generation of oxygen gas during the decomposition of hydrogen peroxide by the microreactors made of tubular catalytic nanomembranes has recently attracted considerable attention. Catalytic microtubes play simultaneous roles of the oxygen bubble producing microreactors and oxygen bubble-driven micropumps. An autonomous pumping of peroxide fuel takes place through the microtubes by the recoiling microbubbles. Due to optimal reaction–diffusion processes, gas supersaturation, leading to favorable bubble nucleation conditions, strain-engineered catalytic microtubes with longer length produce oxygen microbubbles at concentrations of hydrogen peroxide in approximately ×1000 lower in comparison to shorter tubes. Dynamic regimes of tubular nanomembrane-based oxygen microbubble generators reveal that this depends on microtubes’ aspect ratio, hydrogen peroxide fuel concentration and fuel compositions. Different dynamic regimes exist, which produce specific bubble frequencies, bubble size and various amounts of oxygen. In this study, the rolled-up Ti/Cr/Pd microtubes integrated on silicon substrate are used to study oxygen evolution in different concentrations of hydrogen peroxide and surfactants. Addition of Sodium dodecyl sulfate (SDS) surfactants leads to a decrease of bubble diameter and an increase of frequencies of bubble recoil. Moreover, an increase of temperature (from 10 to 35 °C) leads to higher frequencies of oxygen bubbles and larger total volumes of produced oxygen.

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“…For touch sensors on conventional electronic devices, standard manufacturing practices involve high-resolution printing, weaving, or semiconductor-based fabrication of wired grids. [19][20][21][22] Developments and applications in papertronics have included transistors, [23][24][25][26] energy storage and harvesting, [27][28][29][30] pressure sensors, [12,31] force sensors, [32] touch sensors, [33] digital logic, [34,35] sanitizers, [18] oxygen generation, [36] fuel cells, [37] metamaterial-based chemical detection, [38] and electrochemical detectors. When the sensing area does not have overlapping wires, the number of discrete sensing locations scales linearly with the number of wired leads connecting to the keypad or www.advelectronicmat.de arrayed capacitive sensors.…”

Section: Introductionmentioning

confidence: 99%

“…Paper, as a material, continues to receive attention as a substrate for low‐cost flexible electronics . Developments and applications in papertronics have included transistors, energy storage and harvesting, pressure sensors, force sensors, touch sensors, digital logic, sanitizers, oxygen generation, fuel cells, metamaterial‐based chemical detection, and electrochemical detectors …”

Section: Introductionmentioning

confidence: 99%

Paper‐Based Resistive Networks for Scalable Skin‐Like Sensing

Zou

Chen

Liang

et al. 2018

Adv Elect Materials

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user interface. In other words, increasing resolution or adding sites for the detection of touch, generally requires augmenting the number of interconnects. With the exception of using a single electrode-based sensing technique to make natural and inanimate objects become user interfaces, there has been a lack of effort in the reduction of the number of wired leads required for scalable sensing of touch. [9] In contrast to electronic touch sensors, skin on humans/vertebrates uses hierarchical neural networks to transmit the relative spatial detection and intensity of force on fleshy surfaces to the brain. [10] These neural networks do not depend on having a pair of running wires for each location. Instead, they have developed mechanisms for sending spatial information about touch along the spinal cord. Inspired by this concept, Tee et al. presented a skininspired organic digital mechanoreceptor, which converted force-based stimuli into digital signals with varied frequencies to mimic the communication between biological mechanoreceptors and the brain. [11] Similarly, there are opportunities to build electrical networks to reduce the number of wired leads required for spatial detection of touch on synthetic electronic skins.The advancements in skin-like sensing with flexible electronics have moved toward the design and fabrication of active electronic components arrayed on flexible sheets with surface areas less than 10 cm in diameter. [12][13][14][15][16] For example, Someya and co-workers demonstrated an application of thin-film transistors in skin-like sensors capable of measuring distributed pressures over a 9 cm × 9 cm footprint. [12] The size of the sensors is typically dependent on the method of fabrication, and current skin-like sensors often cover small areas (i.e., much less area than that of human skin) because of the limited size of semiconductor-based wafers. As mentioned previously, the number of wired leads in conventional arrays of skin-like sensors increases with the square root of the number of buttons. While this scaling may appear favorable, there are still difficulties with making large sensing grids, as a larger quantity of traces requires more space for wired connections and multiplexed measurements.In this work, we present an approach to passive sensing for skin-like sensors consisting of tunable resistive networks and This work presents a unique approach to the design, fabrication, and characterization of paper-based, skin-like sensors that use patterned resistive networks for passive, scalable sensing with a reduced number of interconnects. When touched or wetted with water, the sensors in the resistive networks detect significant changes in electrical impedance. Fabricating these resistive networks and sensors in a single sheet of metallized paper reduces the number of distinct inputs/outputs to the arrayed sensors. For human-electrode interactions, circuit-based models guide the design/material processing of the resistive networks and selection of operating frequencies-typically ranging...

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A paper-based oxygen generating platform with spatially defined catalytic regions

Cited by 23 publications

References 26 publications

Breathing life into engineered tissues using oxygen-releasing biomaterials

Breathing life into engineered tissues using oxygen-releasing biomaterials

Parameters Optimization of Catalytic Tubular Nanomembrane-Based Oxygen Microbubble Generator

Paper‐Based Resistive Networks for Scalable Skin‐Like Sensing

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