A Partial Mongol

A Preliminary Note on a Case of Trisomic Down's Syndrome with a Short Arm Deletion of a G Group (21-22) Chromosome

“…The karyotypephenotype relationship observed in the present case, as well as in cases presented by Shaw (1962) and Dent et al (1963), seems to suggest that a trisomic condition for the long arm of one of the G group chromosomes is possibly associated with the occurrence of Down's syndrome.…”

“…On the other hand, Dent et al, (1963) described a case of atypical Down's syndrome who had 47 chromosomes with a deletion [Vol. 42, of half the long arm of the extra small element.…”

Dermatoglyphic Study of Six Patients with the XYY Syndrome

“…The frequency of arch pattern was 15.5% in the pooled 11 XYY patients, including the six patients from the present study [F raccaro et al, 1962;Dent et al, 1963;UcniDA et al, 1964;P ersson, 1967], compared with 4.9% in the control group of males studied by Cum mins and Midlo [1961] …”

Trisomy 21 with Borderline Mental Retardation

“…None of these patients had a congenital heart lesion or any other m ajor m alform ation. The IQs, recorded in four of these five cases, were 67 [22], 70 [4], 80 [23], and 86 [7]. Thus, a low-normal IQ can be found in individuals who have only a fragm ent of an extra Gm chromosome in their karyotype.…”

“…Only a few such cases have been reported [4,7,9,22,23]. The mongoloid features of these patients were not too obtrusive, and prom pted diagnoses such as atypical mongoloid [22], mongoloid exhibiting m inimal mongoloid stigm ata [9], partial mongoloid [4], normal indi vidual with numerous mongoloid stigm ata [23], and mongoloid with exceptional intelligence [7].…”