Water’s low viscosity renders it a poor lubricant, but its green footprint, non-toxicity, inflammability, and low cost make it a desirable hydraulic fluid. Axial piston machines running on water are commercially available, but, especially the larger units, do not operate in the high-pressure regime ( ≥300 bar). The present work investigates micro surface shaping as a design solution for the critical piston–cylinder interfaces of these units, which are particularly hard-struck by the low viscosity of water in that the pistons are subject to a heavy side load, and these interfaces cannot be hydrostatically balanced. Through virtual prototyping, the effect of two surface shapes at a high-pressure operating condition is studied for the case of a 75 cc commercial unit: first, the concave bore profile, which gives the bore surfaces through which the pistons travel the lengthwise cross-section of a circular arc, and second, the barrel piston profile, which bestows this cross-section on the piston running surface instead. The design studies conducted show that, on account of the manner in which the pistons of these machines deform over the high-pressure stroke, the concave bore profile is most able to improve overall load support when its apex is in the middle of the guide length, or shifted toward the displacement chamber. Furthermore, the concave bore profile outperforms the barrel piston profile, largely because when the piston’s axial movement takes its apex into the displacement chamber, this surface shape is no longer able to enhance the piston-bore surface conformity at the end of the interface bordering the displacement chamber that is conducive to hydrodynamic pressure buildup in that region.