A Patient-specific Knee Joint Computer Model Using MRI Data and 'in vivo' Compressive Load from the Optical Force Measuring System

Potočnik, Božidar; Zazula, Damjan; Cigale, Boris; Heric, D.; Cibula, Edvard; Tomazic, Tomaz

doi:10.2498/cit.1001126

Cited by 10 publications

(9 citation statements)

References 21 publications

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“…The knee joint is one of the largest and most heavily loaded joints of the human body during daily activities [ 18 ]. The fixation device of HTO surgery is used to stabilize the opening and enhance bone union.…”

Section: Discussionmentioning

confidence: 99%

Biomechanical evaluation of high tibial osteotomy plate with internal support block using finite element analysis

Yang

Lin

et al. 2021

PLoS ONE

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Background/Objective High tibial osteotomy (HTO) is a common treatment for medial knee arthrosis. However, a high rate of complications associated with a plate and a significant loss of correction have been reported. Therefore, an internal support block (ISB) is designed to enhance the initial stability of the fixation device that is important for successful bone healing and maintenance of the correction angle of the osteotomy site. The purpose of this study was performed to examine if an internal support block combined with a plate reduces the stress on the plate and screw area. Methods Finite element models were reconstructed following three different implant combinations. Two loading conditions were applied to simulate standing and initial sit-to-stand postures. Data analysis was conducted to evaluate the axial displacement of the posteromedial tibial plateau, which represents the loss of the posteromedial tibial plateau in clinical observation. Moreover, the stresses on the bone plate and locking screws were evaluated. Results Compared to the TomoFix plate, the ISB reduced the axial displacement by 73% and 76% in standing and initial sit-to-stand loading conditions, respectively. The plate with an ISB reduced stress by 90% on the bone plate and by 73% on the locking screw during standing compared to the standalone TomoFix plate. During the initial sit-to-stand loading condition, the ISB reduced the stress by 93% and 77% on the bone plate and the locking screw, respectively. Conclusion The addition of the PEEK block showed a benefit for structural stability in the osteotomy site. However, further clinical trials are necessary to evaluate the clinical benefit of reduced implant stress and the internal support block on the healing of the medial bone tissue.

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Section: Discussionmentioning

confidence: 99%

Biomechanical evaluation of high tibial osteotomy plate with internal support block using finite element analysis

Yang

Lin

et al. 2021

PLoS ONE

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“…The material models used byÖhman et al [13] are generally better than those of Potočnik et al [12]. The menisci material is represented by the neo-Hookean hyperelastic material model.…”

Section: Subject-specific Modelsmentioning

confidence: 99%

“…One model, by Potočnik et al [12], was made with the intriguing goal of being easily adaptable to the unique knee geometries of different people. The paper outlines a procedure for using magnetic resonance imaging to take a sparse sequence of fast twodimensional images at several knee flexions and loads.…”

Section: Subject-specific Modelsmentioning

confidence: 99%

“…Finally, a template knee mesh is mapped onto the subject-specific geometry. This template mesh is constructed once from high-quality imaging data; by mapping it onto the subject's knee joint geometry, a high-quality subject-specific mesh results [12].…”

Section: Subject-specific Modelsmentioning

confidence: 99%

“…However, the resulting model is limited by the material models used. Bones, menisci, cartilage, and ligaments are all treated as linear-elastic isotropic materials [12]; though these are simple material models that can effectively model many metals, it is well known that many biological tissues exhibit non-linear, anisotropic behaviour [1]. Furthermore, though the geometry can be tailored to individual subjects, the material properties cannot without far more invasive testing; they are simply set to match those of the template.…”

Section: Subject-specific Modelsmentioning

confidence: 99%

See 2 more Smart Citations

Finite element analysis of knee articular cartilage

Heydon¹

2021

Preprint

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The knee joint is often subjected to high loads, which can lead to injury and osteoarthritis. To better understand its behaviour, a finite element model of the joint was created. A hyperelastic material model was created to represent articular cartilage. A six parameter Ogden curve was fiitted against experimental stress-stretch data of cartilage. This material was applied to two different finite element models of the knee created from anatomical slice images. The complete models were validated against data from experiments performed on whole knees. Under compressive loading, the deflection of the model joints were found to be within one-half of a standard deviation of the experimental data. One model was tested in alternate configurations; its response was found to be strongly related to cartilage thickness and knee flexion. Therefore, it is concluded that this cartilage material model can be used to accurately predict the load response of knees.

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Generating finite element models of the knee: How accurately can we determine ligament attachment sites from MRI scans?

Rachmat

Janssen

Zevenbergen

et al. 2014

Medical Engineering & Physics

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In this study, we evaluated the intra- and inter-observer variability when determining the insertion and origin sites of knee ligaments on MRI scan images. We collected data of five observers with different backgrounds, who determined the ligament attachment sites in an MRI scan of a right knee of a 66-year-old male cadaver donor. We evaluated the intra- and inter-observer differences between the ligament attachment center points, and also determined the differences relative to a physical measurement performed on the same cadaver. The largest mean intra- and inter-observer differences were 4.30mm (ACL origin) and 16.81mm (superficial MCL insertion), respectively. Relative to the physical measurement, the largest intra- and inter-observer differences were 31.84mm (superficial MCL insertion) and 23.39mm (deep MCL insertion), respectively. The results indicate that, dependent on the location, a significant variation can occur when identifying the attachment site of the knee ligaments. This finding is of particular importance when creating computational models based on MRI data, as the variations in attachment sites may have a considerable effect on the biomechanical behavior of the human knee joint.

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A Patient-specific Knee Joint Computer Model Using MRI Data and 'in vivo' Compressive Load from the Optical Force Measuring System

Cited by 10 publications

References 21 publications

Biomechanical evaluation of high tibial osteotomy plate with internal support block using finite element analysis

Biomechanical evaluation of high tibial osteotomy plate with internal support block using finite element analysis

Finite element analysis of knee articular cartilage

Generating finite element models of the knee: How accurately can we determine ligament attachment sites from MRI scans?

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