A patient with ankylosing spondylitis and recurrent haemoptysis

Franquet, Tomás; Müller, Néstor L.; Flint, Julia

doi:10.1183/09031936.04.00042804

Cited by 11 publications

(7 citation statements)

References 9 publications

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“…Two case reports [7,8] of aspergillosis developing in fibrocavitary lesion in ankylosing spondylitis have appeared. Franquet et al [7] described a 57-year-old patient with long-standing ankylosing spondylitis who presented with fever, dyspnea and recurrent hemoptysis. The chest radiograph showed extensive scarring of upper lobes and a cavitary containing an ovoid mass in the left upper lung.…”

Section: Upper Lobe Fibrosismentioning

confidence: 95%

Pulmonary involvement in ankylosing spondylitis

Quismorio

2006

Current Opinion in Pulmonary Medicine

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The clinical significance of the high-resolution computed tomography abnormalities remains to be determined. Most of the published studies are cross-sectional, and are limited by lack of control subjects matched for age, gender and tobacco use. Studies to correlate high-resolution computed tomography changes with bronchoalveolar lavage and lung biopsies as well as prospective studies on long-term evolution of these findings including those patients receiving anti-tumor necrosis factor-alpha agents are needed.

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Section: Upper Lobe Fibrosismentioning

confidence: 95%

Pulmonary involvement in ankylosing spondylitis

Quismorio

2006

Current Opinion in Pulmonary Medicine

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“…Aspergilloma AS'li hastalarda görülen en sık form olup kronik nekrotizan pulmoner aspergilozis formları nadir olarak görülmektedir. Klinik olarak genelde asemptomatik olmalarına rağmen öksürük ve tekrarlayan hemoptizi ataklarıyla başvurabilirler [1,9]. Radyolojik özelliklerinin tüberküloz ve maligniteye benzemesi nedeni ile ayırıcı tanısının yapılması gerekmektedir [10,11].…”

Section: Discussionunclassified

“…AS'li hastaların %2'sinden daha azında akciğer tutulumu görülmektedir [8,9]. Radyolojik olarak akciğer tüberkülozu ve maligniteyi taklit edebilir.…”

Section: Introductionunclassified

Chronic Necrotizing Pulmonary Aspergillosis in a Case with Ankylosing Spondylitis

Perinçek¹,

Hatipoğlu²,

Yörük³

et al. 2012

Tur Toraks Der

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Ankylosing spondylits is a prototype of spondyloarthropathy tropates. During the progression of ankylosing spondylitis, which can destroy many systems, pleuroparanchymal involvement occurs rarely. The most commonly observed lesion is the fibrobullous disease on the upper lobes. Chronic aspergillus colonization has been reported in a quite significant percentage of the patients with ankylosing spondylits (50-65%). Pulmonary aspergilloma is the most observed clinical form in patients with ankylosing spondylitis. Invasive pulmonary aspergillosis occurs especially in patients with immunesupression. Here we shall present a case with ankylosing spondylitis complicated by chronic necrotizing pulmonary aspergillosis which is a form of invasive pulmonary aspergillosis. (Tur Toraks Der 2012; 13: 83-6) ÖZETAnkilozan spondilit, spondiloartropatilerin prototipidir. Pek çok sistemi tutabilen ankilozan spondilitin seyrinde, plöroparankimal tutulum nispeten nadir görülür. En sık gözlenen lezyon üst loblardaki fibro-büllöz hastalıktır. Ankilozan spondilitli hastaların oldukça önemli bir kesiminde (%50-65) kronik aspergillus kolonizasyonu bildirilmektedir. Pulmoner aspergilloma, ankilozan spondilitli hastalarda en sık görülen klinik form olup, invaziv pulmoner aspergillosis özellikle immunsistemi baskılanmış olan hastalarda görülür. Biz burada invaziv pulmoner aspergillosisin bir formu olan kronik nekrotizan pulmoner aspergillosis gelişen ankilozan spondilitli bir olguyu sunacağız.

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“…Franquet et al 6 described the case of a patient with AS for 15 years with hemoptysis, progressive dyspnea, weight loss, and fever. The patient denied history of tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

Infecção fúngica pulmonar por hialo-hifomicose associada a zigomicose e Actinomyces spp. em paciente com espondilite anquilosante

Azevedo

Felippe²,

Silva³

et al. 2009

Rev. Bras. Reumatol.

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Ankylosing spondylitis (AS) can be associated with extra-articular manifestations, among which we find pulmonary disorders. Fibrosis of the pulmonary apices is seen in up to 30% of the cases, and cyst formation is less common, being seen in advanced cases. Colonization of those cavities is a rare complication. A patient with a diagnosis of AS since 1998 with axial involvement and history of pulmonary tuberculosis treated in 2002 and 2007, developed bilateral aspergillosis of the pulmonary apices associated with zygomycosis and Actinomyces spp. The patient had been hospitalized to investigate complaints of weight loss, nocturnal diaphoresis, productive cough, and lesion in both lung apices. He was submitted to right upper pulmonary lobectomy after identification of a fungus ball on chest X-ray and CT scan, which was confirmed by a fibrobronchoscopy and biopsy for anatomopathological exam. The patient evolved without expansion of the right lung and underwent another fibrobronchoscopy that suggested occlusion of the middle lobar bronchus. Repeat thoracotomy did not confirm the findings of the last fibrobronchoscopy, but the right lung failed to expand. The patient developed septic shock refractory to treatment and died.

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A patient with ankylosing spondylitis and recurrent haemoptysis

Cited by 11 publications

References 9 publications

Pulmonary involvement in ankylosing spondylitis

Pulmonary involvement in ankylosing spondylitis

Chronic Necrotizing Pulmonary Aspergillosis in a Case with Ankylosing Spondylitis

Infecção fúngica pulmonar por hialo-hifomicose associada a zigomicose e Actinomyces spp. em paciente com espondilite anquilosante

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