“…Notably, diagnosing a case of IS based on the mechanism of thrombosis developing to fill the lumen of an unruptured aneurysm and invading the parent artery is not simple for several reasons. First, the imaging of a completely thrombosed aneurysm is difficult to distinguish from other lesions, especially brain tumors [6 , [15] , [16] , [17] , [18] ] and cavernoma [5 , [19] , [20] , [21] ]. Even the “gold standard” for diagnosing cerebrovascular disease, digital subtraction angiography (DSA), is also difficult to distinguish and the results are usually “negative”.…”