A persistent dermal hypersensitivity reaction associated with Helicobacter pylori infection

Development of delayed dermal hypersensitivity reaction following the second dose of COVID‐19 vaccine – A series of 37 cases

“…2 CLLs related to COVID-19 infection have been widely documented in mild symptomatic or asymptomatic children and adolescents. 3 Among different pathogenetic hypothesis, the role of cytokine-mediated inflammatory response and endothelial damage induced by obliterative microangiopathy caused by Sars-CoV-2 seem to be the most accredited. 4 We assume that, likewise onychomadesis induced by Coxsackievirus, the imbalance between inflammation and direct virus damage could be responsible for nail discharge in our case.…”

“… 1 , 2 Dermal hypersensitivity reaction is one such reaction pattern. Clinically, the lesions of dermal hypersensitivity reaction are characterized by papular urticaria‐like eruptions lasting for longer than 24 h. 3 Eruptive pseudoangiomatosis (EPA) is a variant of dermal hypersensitivity reaction consisting of benign, self‐limiting exanthematous lesions. The lesions of EPA are pinpoint erythematous macules and urticarial papules having a blanched perilesional halo.…”

“…This is of particular relevance in terms of patient counselling and physician endorsement, considering that SARS-CoV-2 vaccine hesitancy is prevalent across the AIBD population (approximately one third), with concern regarding immunobullous exacerbation representing a major factor contributing to hesitancy. 3…”