A personalized and automated dbSNP surveillance system

Motivation: Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation in humans. However, the factors that affect SNP density are poorly understood. The goal of this study was to estimate the relative effects of mutability and selection on SNP density in transcribed regions of human genes. It is important for prediction of the regions that harbor functional polymorphisms.

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Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome

Gorlov

Gorlova

Amos

2008

BMC Genomics

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A personalized and automated dbSNP surveillance system

Cited by 1 publication

References 12 publications

Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome

Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome

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