A Pharmacist-based Screening Program of Octogenarians Starting New Medications

Seevak, Evan; Kent, Daniel L.; Wagner, Edward H.

doi:10.18553/jmcp.2003.9.1.13

Cited by 6 publications

(4 citation statements)

References 21 publications

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“…Providers should try to ensure that patients at risk fully understand instructions for using their medications and are able to recognize and report early signs of adverse events. An additional strategy is to engage the clinical pharmacist in the care of these high‐risk patients 28 . Computerization of prescribing and monitoring probably represents the most potent prevention strategy, 10 although its effect in the ambulatory setting has not been adequately evaluated.…”

Section: Discussionmentioning

confidence: 99%

“…An additional strategy is to engage the clinical pharmacist in the care of these high-risk patients. 28 Computerization of prescribing and monitoring probably represents the most potent prevention strategy, 10 although its effect in the ambulatory setting has not been adequately evaluated. The findings of the current study suggest that it will be important to link computerized physician order entry systems to electronic files containing patient-specific data so that decision support systems can identify patients at risk.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Risk Factors for Adverse Drug Events Among Older Adults in the Ambulatory Setting

Field

Gurwitz

Harrold

et al. 2004

J American Geriatrics Society

254

185

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Risk Factors for Adverse Drug Events Among Older Adults in the Ambulatory Setting

Field

Gurwitz

Harrold

et al. 2004

J American Geriatrics Society

254

185

View full text Add to dashboard Cite

show abstract

“…Even in elderly patients with perceived contraindication, ACE inhibitor use was associated with a significant survival benefit [131]. In one pharmacist‐based pilot study of 48 octogenarians prescribed medications, 14 experienced undesirable effects while six had an inadequate effect [132]. This finding does not argue for a lower dose requirement in the elderly.…”

Section: Determining the Right Dose In The Elderlymentioning

confidence: 99%

Drug development and use in the elderly: search for the right dose and dosing regimen

Shah¹

2004

Brit J Clinical Pharma

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Across the globe over the last few decades, there has been a remarkable increase in the proportion of the population which is elderly, and this trend is set to continue. Data from 10 countries that accounted for about 55% of the world population of 6079 million in the year 2000 provide an overview of this significant shift in demography. Table 1 summarizes the projections for the next 25 years. Hitherto, increases in life expectancy have been most obvious in the affluent countries; however, improvements in public health and disease control are also leading to increases in life expectancy in the less affluent countries. As a result of relatively larger increases in life expectancy at birth, significant shifts in demography are also expected in countries that are at present economically less affluent. The number of elderly people in the world is therefore expected to continue to increase for some considerable time. Interestingly, the most dramatic increases in the proportion of the population who are elderly are anticipated in countries where total populations are projected to decrease (such as Japan, Germany and Italy).The 2001 population census of the UK revealed that since the census of 1951, the proportion of elderly population above 65 years and 85 years has increased from 16% and 0.4% respectively to 21% and 1.9%, respectively. These changes in demography will have significant effects on the economics generally as well as on the provisions for healthcare. Cardiovascular and neurological diseases and cancers are the most prevalent in the elderly. These three groups of diseases account for about 54% of the total burden of disease in Europe in terms of disability adjusted life years. Of the total gross Hospital and Community Health Services expenditure of £31.9 billion in the year 2001-2002 in the UK, 13% was expended on people aged 65-74 years, 16% on those aged 75-84 years and 10% for people aged 85 years or more. Furthermore, about 55% of the community prescriptions during 2001 in the UK were dispensed for the elderly. Cardiovascular and psychoactive drugs accounted for more than 40% of these prescriptions. In view of many age-related changes in the pharmacokinetics and pharmacodynamics of a drug, the safe and effective prescribing of medicines in the elderly will continue to present a major challenge.This review provides an overview of the issues relevant to development and clinical use of drugs in the elderly population, with particular reference to determining the right dosage and dose regimen and the regulatory requirements that facilitate this process. It also examines whether, as a result of advancing age per se, the dosing regimens in the elderly and the frail elderly might be different from those in the nonelderly.

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“…O referido cenário tem elevado a demanda por cuidados específicos e requer que as ILPIs deixem de fazer parte apenas da rede de assistência social e integrem a de assistência à saúde. [4][5][6] Segundo a literatura médica, o trabalho da equipe multiprofissional de saúde é fundamental para o cuidado de idosos, pois pode prover oportunidades substanciais à melhora na qualidade do tratamento dessa população. [7][8][9] Além disso, como membro dessa equipe, os farmacêuticos veem buscando, sob diferentes formas, reduzir custos e aumentar a efetividade dos tratamentos em ILPIs.…”

Section: Introductionunclassified

Implantação estrutural de serviços farmacêuticos em instituições de longa permanência para idosos: estudo piloto

Silva¹,

Oliveira²,

Santos³

et al. 2015

Geriatr. Gerontol. Aging

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OBJETIVO: Descrever a implantação estrutural de um modelo de serviços farmacêuticos a instituições de longa permanência para idosos. MÉTODOS: O estudo traça a implantação estrutural de um modelo de serviços farmacêuticos em uma instituição de longa permanência para idosos, no município de Aracaju, em Sergipe, realizada de janeiro de 2010 a dezembro de 2012. Os indicadores de qualidade de estrutura foram avaliados por um farmacêutico-pesquisador e um farmacêutico-auditor, com base na adaptação de resolução da Agência Nacional de Vigilância Sanitária e em recomendações da literatura internacional. Ao final do estudo, conduziu-se uma comparação entre os indicadores, antes e após a implantação. RESULTADOS: De acordo com o roteiro de tal órgão, após as intervenções farmacêuticas, houve modificação em sete dos 13 indicadores de qualidade nas instituições de longa permanência para idosos. O segundo instrumento demonstrou modificação de dois dos dez indicadores de qualidade em tais locais. Já no terceiro, houve modificação em seis dos 11 indicadores de qualidade após as intervenções farmacêuticas. Embora as avaliações tenham sido centradas nas características estruturais do sistema de uso de medicamentos, alguns dos indicadores modificados estavam relacionados a atividades que caracterizam "processos", tais como armazenamento e controle de estoque. A principal estratégia empregada foi a implantação de um dispensário de medicamentos em instituições de longa permanência para idosos, que permitiu o armazenamento adequado dos medicamentos e possibilitou a disponibilização das fontes de informação. CONCLUSÃO: A implantação dos serviços farmacêuticos em instituições de longa permanência para idosos possibilitou a alteração das características estruturais do sistema de uso de medicamentos nela. PALAVRAS-CHAVE: instituição de longa permanência para idosos; atenção farmacêutica; indicadores de qualidade em assistência à saúde.

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A Pharmacist-based Screening Program of Octogenarians Starting New Medications

Cited by 6 publications

References 21 publications

Risk Factors for Adverse Drug Events Among Older Adults in the Ambulatory Setting

Risk Factors for Adverse Drug Events Among Older Adults in the Ambulatory Setting

Drug development and use in the elderly: search for the right dose and dosing regimen

Implantação estrutural de serviços farmacêuticos em instituições de longa permanência para idosos: estudo piloto

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